While olanzapine may help children with autism, it also places them at risk for gaining a large amount of weight.
Atypical antipsychotics have fewer side effects than older antipsychotics. Since there is no medical cure for autism, atypical antipsychotics are sometimes used to help certain symptoms of autism. This study was designed to see whether the atypical antipsychotic olanzapine would help pervasive developmental disorder (PDD) and decrease impulsive and aggressive actions. Half of the children tested showed significant improvements in symptoms of autism. The authors note that the study was only eight weeks long.
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