Memantine (0.4 mg/kg) may help the memory and behavior of children with autism.
Memantine is used for the treatment of Alzheimer's disease. This was an open-label study, which means that the doctors, the parents, and the children all knew that the children were being given the drug. While parents thought that the drug helped all of the symptoms of autism (Clinical Global Improvement), the doctors did not notice a difference. The authors suggest that the better memory seen with the drug could have come from changing the brain chemistry or could have come from helping the child to pay attention. The authors note that it is difficult to know what dose of the drug to give children.
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