Research: ß-Casomorphin Induces Fos-Like Immunoreactivity in Discrete Brain Regions Relevant to Schizophrenia and Autism

Authored by Sun, Z., Cade JR, Fregly MJ, and Privette RM in Autism, Volume 3, Issue 1, p. 67-83, (1999).

Article summary (posted Nov 14, 2006):

This article concludes that casomorphine, a by-product of milk digestion, can affect brain areas that are involved in schizophrenia and autism.

The authors outline the evidence that autism and schizophrenia can be explained by high levels of casomorphine in individuals with either disorder. The purpose of this study was to determine the brain areas that are influenced by casomorphine. Rats were injected with one form of casomorphine, and their brains were examined to see which areas were activated, as compared to rats that didnâ??t receive the casomorphine. The results show that the brain regions that were activated by casomorphine were also among those that are affected in people with schizophrenia or autism.

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You can access the original abstract and the complete paper is sometimes available for free via Google Scholar (look for entries that say "PDF").
autism, casein-free diet, casomorphines, digestion, elimination diet, evidence-based medicine (EBM), milk, schizophrenia
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