Effects of Development on Olanzapine-Associated Adverse Events

Source:

J. Am. Acad. Child Adolesc. Psychiatry, Volume 41, Issue 12, p.1439-1446 (2002)

Layperson Summary:

Olanzapine may cause weight gain and sedation in children.

Olanzapine is an atypical antipsychotic that is increasingly prescribed to children and teenagers with pervasive developmental disorders, obsessive-compulsive disorder, and mental retardation. This study was designed to determine whether or not there are any side effects from olanzapine that are specific to children and adolescents (as opposed to adults). The authors found that weight gain and sedation may occur more often in children and teenagers than in adults. In addition, children may have more tardive dyskinesia than adults. Tardive dyskinesia is the medical term for repetitive and involuntary movements. The authors suggest that doctors look closely for these side effects in children given olanzapine.

Scientific Abstract

page last updated 12/08/2006

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