Enviromimetics: Exploring Gene-Environment Interactions to Identify Therapeutic Targets for Brain Disorders

Source:

Expert Opin. Ther., Volume 11, Issue 7, p.1-14 (2007)

Layperson Summary:

Enviromimetics is a new word that is used to describe drug therapies that are designed to mimic or enhance the good effects of a rich environment. This review article describes how enviromimetics could be used to help many diseases, including autism. The authors of this paper are trying to develop new brain drugs by targeting the chemical changes that happen when the brain is exposed to a rich environment. Right now they are testing this in mice in hopes of finding a drug that causes the same brain changes that are found when un-drugged mice are placed in a stimulating environment. The authors are also looking to see if drugs that are already being sold may have this effect. One such drug that they are looking at is Enviromimetics describes drug therapies designed to mimic effects of a rich environment on the brain. The studies were done on mice. Fluoxetine might work.(a selective serotonin reuptake inhibitor (SSRI)).

Scientific Abstract

page last updated 09/08/2007

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