Research: Glutamate Antagonists Seem to be Slightly Effective in Psychopharmacologic Treatment of Autism

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Authored by Niederhofer, H. in Journal of Clinical Psychopharmacology, Volume 27, Issue 3, p. 317-318, (2007).

Article summary (posted Jun 21, 2007):

Memantine therapy may help people with autism.

Drugs such as memantine are normally used to treat Alzheimer'??s disease (cholinergic drugs). This is a small report on the use of memantine therapy in four patients (children and adults) with autism. The patients received 20 mg memantine daily for four weeks. Patients did not seem to have headaches or stomachaches. The author found that treatment with memantine helped the patients feel less irritable.

Links:

You can access the original abstract and the complete paper is sometimes available for free via Google Scholar (look for entries that say "PDF" or "HTML" on the right side of the page).
adults with autism, autism, cholinergic, drug, glutamate, Namenda (memantine hydrochloride), therapy, treatment
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