Increased Excretion of a Lipid Peroxidation Biomarker in Autism

Source:

Prostaglandins, Leukotrienes and Essential Fatty Acids, Volume 73, p.379-384 (2005)

Layperson Summary:

This article suggests that autism may be associated with oxidative stress that results from difficulties in managing free radicals in the body.

The authors tested 33 children with autism (ages not given) and 29 controls for biomarkers for oxidative stress. They report that children with autism had a biomarker for oxidative stress (isoprostane) that was significantly higher than in controls. This biomarker shows that cell membranes in the body and/or brain are likely to have been damaged by free radicals. The authors conclude that children with autism may be genetically more likely to develop oxidative stress, supporting the use of anti-oxidants such as vitamin C in autism.

Scientific Abstract

page last updated 11/13/2006

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