Is Methylphenidate a Safe and Effective Treatment for ADHD-like Symptoms in Children with Pervasive Developmental Disorders?

Source:

Expert Opinion in Pharmacotherapy, Volume 8, Issue 7, p.1025-1028 (2007)

Layperson Summary:

Methylphenidate may not be the best choice for children with pervasive developmental disorder (PDD) who also have symptoms of attention deficit hyperactivity disorder (ADHD).

Many doctors prescribe methylphenidate to treat symptoms of ADHD in children with autism. The authors reviewed a recent study (known as the RUPP MPH Study) on whether or not methylphenidate therapy works for children with autism. They found that the RUPP MPH study was well-designed and well-done. Most of the children in the study were boys (89%). The authors found that most children with autism stopped taking methylphenidate because they did not like the side effects. So, even though methylphenidate does work in children with autism, it does not work as well as it does in children who do not have autism.

Scientific Abstract

page last updated 08/01/2007

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