Research: The Neuropathology, Medical Management, and Dental Implications of Autism

Authored by Friedlander, AH, Yagiela JA, Paterno VA, and Mahler ME in Journal of the American Dental Association, Volume 137, Issue 11, p. 1517-1527, (2006).

Article summary (posted Nov 23, 2006):

Parents should communicate to dentists any drugs that have been prescribed to the child as the drugs may have orofacial side effects and/or may interact with any drugs prescribed by the dentist.

For example, risperidone and olanzapine may cause problems with speech, swallowing, and the use of retainers. Fluoxetine and sertraline may cause diarrhea, nausea, and possibly changes in the speed at which blood clots. In addition, fluoxetine and sertraline may interact with other drugs prescribed by the dentist including codeine, erythromycin, and clarithromycin. Carbamazepine and valproate may also have a negative effect on the ability of blood to clot. Clonidine may magnify the effects of any pain killers used during a dental procedure or in recovery from a procedure.

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You can access the original abstract and the complete paper is sometimes available for free via Google Scholar (look for entries that say "PDF" or "HTML" on the right side of the page).
adverse effects, autism, Carbatrol - Equetro - Tegretol (carbamazepine), Catapres - Duraclon (clonidine), communication, dentist, Depakene (valproic acid), diarrhea, drug, interaction, pain, parent, Prozac - Sarafem (fluoxetine hydrochloride), Risperdal (risperidone), sertraline, speech therapy, swallowing, Zoloft (sertraline hydrochloride), Zyprexa (olanzapine)
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