Research: Olanzapine in the Treatment of Behavioral Problems Associated with Autism: An Open-Label Trial in Kuwait

Authored by Fido, A., and AlSaad S. in Medical Principles and Practices, Volume 17, Issue 5, p. 415-418, (2008).

Article summary (posted Oct 8, 2008):

Olanzapine may help some children with autism with the symptoms of irritability, withdrawal, and hyperactivity.

Over half of children with autism are easily irritated, withdrawn, and hyperactive. This open-label trial study was designed to test the effects of olanzapine on the treatment of these behavior problems of children with autism. The children (all boys) were between the ages of 7 and 17. The 40 children in the study did not seem to have side effects to the olanzapine during the short (13 week) trial. Olanzapine acts on the brain and is known as an atypical antipsychotic.

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You can access the original abstract and the complete paper is sometimes available for free via Google Scholar (look for entries that say "PDF").
adverse effects, antipsychotic, atypical antipsychotic, autism, drug, hyperactivity, irritability, Prozac - Sarafem (fluoxetine hydrochloride), treatment, withdrawal, Zyprexa (olanzapine)
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