Treatment with oral immunoglobulin may improve gastrointestinal (GI) symptoms and behavior in children with autism.
About one quarter of children with autism have GI problems such as diarrhea or constipation. The twelve children in the study were fed nightly doses of 420 mg of immunoglobulin for eight weeks. Earlier studies have shown that about 50% of immunoglobulin that is eaten is biologically active in the gut. The study measured effect of immunoglobulin therapy on stool number, stool texture, and stomach tenderness. Oral immunoglobulin appeared to be safe treatment option for autism.
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