CYP2D6 | hormone | prolactin | puberty | risperidone
Risperidone therapy may cause problems with growth and development in some children.
The purpose of this study was to see if risperidone treatment causes increases in the hormone prolactin. Certain children (CYP2D6 ultrarapid metabolizers) process risperidone differently and respond with higher levels of prolactin. The more risperidone the children are given, the higher the level of prolactin they make. At the end of eight weeks, these sensitive children had prolactin levels that were four-fold higher than untreated children. About 10% of children getting risperidone treatment have levels of prolactin that are considered unsafe.
Or subscribe to feed using a feed reader.
