Research: Risperidone in Children with Autism: Randomized, Placebo-Controlled, Double-Blind Study

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Authored by Nagaraj, R., Singhi P., and Malhi P. in J Child Neurol., Volume 21, Issue 6, p. 450-455, (2006).

Article summary (posted Nov 20, 2006):

Risperidone improves social responsiveness and decreases hyperactivity and aggression in some children with autism.

Risperidone was originally identified as a medication to treat adult schizophrenia. This current study examined a group of 40 children between the ages of 2-9 who were given either risperidone (1 mg/day) or placebo. Fifty seven percent of the children receiving risperidone showed improvement in social responsiveness as well as overall functioning. Eighteen percent of children showed an improvement in aggressive behavior and hyperactivity. Risperidone therapy did not improve speech.

Links:

You can access the original abstract and the complete paper is sometimes available for free via Google Scholar (look for entries that say "PDF" or "HTML" on the right side of the page).
adults with autism, aggressive behavior, autism, double-blind, hyperactivity, medication, placebo, Risperdal (risperidone), schizophrenia, speech therapy, therapy
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