Safety and Usage of Atypical Antipsychotic Medicines in Children: A Nationwide Prospective Cohort Study

Source:

Drug Safety, Volume 30, Issue 7, p.569-579 (2007)

Layperson Summary:

Risperidone use in children with autism may result in sadness.

This New Zealand study looked at the use of a type of drug therapy (atypical
antipsychotics) in children. In 94% of the cases the drug therapy was for risperidone. Risperidone is prescribed for many reasons such as autism, schizophrenia, and bipolar disorders. A total of 131 of the 420 children in the study (31%) had one or more adverse events. The study described one 13-year-old girl with autism who was given risperidone therapy and became sad. An 11-year-old boy with Asperger syndrome received risperidone therapy and became depressed. Another 11-year-old boy with Asperger syndrome had suicidal thoughts after starting risperidone.

Scientific Abstract

page last updated 07/14/2008

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