Autism Therapy: antibiotics

definition of Medication or drug that is used to treat bacterial infections.

Autism Drugs Overview

Published Oct 16, 2009, last updated Feb 28, 2011

A number of drugs are used, with indications and off-label, to treat symptoms associated with autism and additional conditions (comorbidities) associated with autism.  These may include anxiety, epilepsy, and attention deficit disorders.  The only two drugs that have been approved by the US Food and Drug Administraion to treat symptoms related to autism are Risperdal and Abilify.  The drugs in the table below may be given to people on the autism spectrum. Click on the drug name to see all research articles, news, and comments on our site about that drug.

At Healing Thresholds, we believe that a therapy program should be specific to the child and evolve with the child. In some cases, and at some times, a therapy program may include drug therapy. The use of any prescribed medication should be closely monitored by a physician.

Name Generic Name Description
Abilify  aripiprazole This antidepressant was recently approved by the FDA in the United States for the treatment of irritability associated with autistic disorder in pediatric patients 6 to 17 years of age. It is also indicated for treatment of bipolar disorder and schizophrenia in adults and children. Adults are prescribed Abilify as an add-on antidepressant to treat major depressive disorder.
ActoPlus MET pioglitazone hydrocloride and metformin hydrochloride ActoPlus MET is usually prescribed for treatment of diabetes in patients who are not helped by treatment with metformin or pioglitazone alone. This combination medication works by decreasing insulin resistance and by improving sensitivity to insulin in muscle and fat tissue. Pioglitazone is being tested in people with neurological disorders, including autism, because it can also be anti-inflammatory in glial cells in the brain. Preliminary studies showed improvements in behavior in children with autism.
Actos pioglitazone hydrocloride Actos is usually prescribed for treatment of diabetes. Actos works by decreasing insulin resistance, and increasing sensitivity to insulin in muscle and fat tissue. Actos has also been shown to be anti-inflammatory in some conditions. Actos is being tested in people with neurological disorders, including autism, because it can also be anti-inflammatory in glial cells in the brain. Preliminary studies showed improvements in behavior in children with autism.
Adderall amphetamine Adderall XR is the slow release form. Adderall is a central nervous system stimulant that affects chemicals in the brain and in nerves. These brain chemicals (neurotransmitters) regulate activity and impulse control. Adderall is prescribed for attention deficit hyperactivity disorder (ADHD) and narcolepsy (falling asleep). It may also be prescribed off-label for people with autism. Caution: amphetamines have a high potential for abuse. Administration of amphetamines for long periods may lead to drug dependence and must be avoided. Particular attention should be paid to the possibility of subjects obtaining amphetamines for non-therapeutic use or distribution to others, and the drugs should be prescribed or dispensed sparingly. Misuse of amphetamine may cause sudden death and serious cardiovascular adverse events.
Anafranil clomipramine hydrocloride
Anafranil is an antidepressant that may be prescribed off-label for children with autism to help decrease repetitive movements and improve social contacts. It is usually used to treat depression in adults. It is also approved for use in children (at least 8 years old) to treat obsessions and compulsions associated with obsessive compulsive disorder (OCD). This medication is a serotonin reuptake inhibitor, and is a type of tricyclic antidepressant. One possible serious side effect from the drug is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Aricept donepezil hydrochloride Aricept (the generic is donepezil hydrochloride) is indicated for treatment of mild to severe dementia of the Alzheimer’s type. Aricept ODT is the orally disintegrating tablet form of Aricept.  This medication enhances cholinergic function in the brain by reducing the activity of the enzyme acetyl cholinesterase. In people with autism, Aricept or Aricept ODT may help improve attention, learning, and memory. Possible benefits of Aricept or Aricept ODT are being tested in children and adults with autism, ADHD, and schizophrenia.
Ativan lorazepam Ativan is an anti-anxiety medication that may be prescribed for people with autism to help reduce anxiety, and to help reduce symptoms of catatonia (rigid and insensitive muscles). Ativan is indicated for treatment of anxiety disorders, or for short-term treatment of anxiety associated with depression.
Bethanechol bethanechol chloride Bethanechol is prescribed for triggering urination and emptying of the bladder when urine is being retained.
Buspar buspirone hydrochloride Buspar is an antianxiety medication that is indicated for generalized anxiety disorder. Buspar may be prescribed off-label for people with autism to help reduce anxiety and aggression and to help improve behaviors. Buspar has helped improve behaviors in some people with autism. This medication is currently being tested in children and adults with autism.
Carbatrol - Equetro - Tegretol
carbamazepine Carbamazepine is the generic for three brand name drugs, Carbatrol, Equetro, and Tegretol. Carbamazepine can have serious side effects that include a serious skin reaction in people with a certain genetic background, which is more common in Asian and Caucasian (white) people than other groups.

Tegretol is an anticonvulsant medication used to help control seizures. Tegretol may be prescribed for people with autism who have seizures, and can also help soften mood swings. This medication is indicated for treatment of epilepsy and for pain associated with trigeminal neuralgia. The physician should be notified immediately if any rash appears. There is also a risk of agranulocytosis and other changes in blood cells, so the person taking this medication should be monitored with regular blood tests.
 
Carbatrol may be prescribed for people with autism who have seizures, and can also help reduce aggression. This medication is indicated for treatment of epilepsy and for pain associated with trigeminal neuralgia. There is also a risk of agranulocytosis and other changes in blood cells, so the person taking this medication should be monitored with regular blood tests.
 
Equetro is an extended-release formulation of carbamazepine. It is indicated for the treatment of mania in bipolar disorder. Equetro can have serious side effects that include agranulocytosis and other changes in blood cells, so the person taking this medication should be monitored with regular blood tests.
Clozaril - FazaClo clozapine
This is an antipsychotic medication that may be prescribed off-label for children with autism to help reduce hyperactivity, fidgeting, and aggression. Clozapine is the generic and FazaClo® is the orally disintegrating form. Clozaril® lowers binding of dopamine to most types of dopamine receptors and other types of receptors on cells in the nervous system. Clozaril is usually used to treat people with severe schizophrenia, or people who repeatedly threaten to commit suicide. As an uncommon side effect, there is increased risk of seizures or agranulocytosis (a change in white blood cells that can be severe and result in death). The risks are a concern particularly in children and adolescents, and in people who might already have a risk for seizures. The risks also increase with increasing dose of the medication. Other side effects can also occur. People taking Clozaril need to be carefully monitored with regular blood tests for possible side effects.
Concerta methylphenidate hydrochloride Some children with autism also have ADHD and this drug may be helpful in treating the symptoms of ADHD. Concerta is a stimulant that is approved in the United States for the treatment of attention deficit hyperactivity (ADHD) disorder. It is understood that drug therapy is typically only one aspect of a treatment plan to help a child overcome symptoms of ADHD.
Depakene valproic acid
Depakene is available in capsule and syrup forms, this is an anticonvulsant used to treat epilepsy. This medication affects the way that cells get signals to turn on and off in the nervous system. This medication can have serious side effects, especially in children. People with autism who also have seizures might be prescribed this medication. Anti-seizure medicines may not completely eliminate seizures but might reduce the number of seizures. Doses and blood levels of this medication often need to be watched closely by a doctor or other health care professional.
Depakote divalproex sodium
Depakote is an anticonvulsant used to treat epilepsy. This medication affects the way that cells get signals to turn on and off in the nervous system. This medication can have serious side effects, especially in children. Depakote is usually prescribed to treat mania in people with manic-depressive disorder, to prevent seizures in people with epilepsy, and to prevent migraines. People with autism who also have seizures might be prescribed this medication. Anti-seizure medicines may not completely eliminate seizures but might reduce the number of seizures. Doses and blood levels of Depakote need to be watched closely by a doctor or other health care professional.
Dexedrine - Dexedrine Spansule dextroamphetamine sulfate Dexedrine is typically prescribed for attention-deficit hyperactivity disorder (ADHD) in children 6-16 years of age and for narcolepsy (falling asleep). The sustained release, Spansule Sustained-Release Capsules, are not recommended for children less than 6 years old. It may also be prescribed off-label for hyperactivity in children with autism and for adults with ADHD. Dextroamphetamine sulfate is an amphetamine that stimulates the brain and nervous system. Caution: Amphetamines have a high potential for abuse and may lead to drug dependence. Particular attention should be paid to the possibility that the amphetamines are being used or given to other people for non-therapeutic use. Also, misuse of amphetamines may cause sudden death and serious cardiovascular (heart-related) adverse events.
Diastat diazepam Diastat is a sedative in a rectal gel form. Diastat is administered to people who are having severe seizures as a short-term treatment. Diastat may be prescribed for people with autism who also have epilepsy, and would usually be administered during the seizure.
Diflucan fluconazole Diflucan is an anti-fungal antibiotic that is prescribed to treat fungus infections in any part of the body. Diflucan is often prescribed to treat fungal infections in people with weak immune systems. Diflucan may be prescribed off-label for children with autism to help relieve their autism symptoms, based on the idea that autism symptoms may be related to fungus infections in children.
Dilantin phenytoin sodium Dilantin is an antiepileptic drug that is indicated for helping to control seizures in children and adults. If a patient would like to stop Dilantin therapy then he or she should do so gradually under a doctor’s supervision in order to avoid seizures.
Endrate edetate disodium
Endrate is administered I.V., and recommended only for severe cases of metal poisoning because of the risk of serious side effects, including death. Endrate chelates or binds calcium and other trace elements such as magnesium and zinc. Endrate is usually prescribed for emergency treatment of hypercalcemia and for control of ventricular arrhythmias (irregular heart rhythms associated with digitalis toxicity in adults. Endrate should not be used in children because of the risk of death, according to the FDA and the CDC. Endrate has been confused with Versenate (edentate calcium disodium), which is used to chelate lead in lead poisoning cases in children. Mistaken administration of Endrate has resulted in death in some children. Any chelation therapy in children should be administered under careful medical supervision.
Eskalith lithium carbonate
Eskalith (lithium carbonate): Eskalith® is an antidepressant that may be prescribed off-label for children with autism. Eskalith is usually used for treatment of mania in individuals with manic-depressive disorder. It works by altering sodium transport in nerve and muscle cells and increasing the break-down of some neurotransmitters. Eskalith CR® is a controlled-release tablet form of lithium. The safety and effectiveness of Eskalith in children with autism has not been proven but it may be helpful for some of them.
Fortamet - Glumetza metformin hydrochloride Fortamet or Glumetza (extended release tablet) is usually prescribed for treatment of type 2 diabetes in people over 17 years of age. Metformin works by decreasing liver glucose production, and increasing sensitivity to insulin in muscle and fat tissue. In people with autism, taking metformin with antipsychotic medications such as risperidone may help reduce weight gain that often occurs as a side effect of the antipsychotic medication.
Geodon ziprasidone
Geodon is an antipsychotic medication that may be prescribed for people with autism to help reduce hyperactivity, aggression, self-abusive behavior, temper tantrums, lability (mood swings), social withdrawal, and repetitive behaviors. Geodon is currently in clinical trials to test effectiveness in children with autism. Some children have improved with treatment. Geodon is indicated for schizophrenia, bipolar mania, and agitation in people with schizophrenia. Geodon works as a dopamine and serotonin type 2 antagonist, and has other effects on the nervous system.
Haldol haloperidol
Haldol is an antipsychotic medication that may be prescribed for some people with autism to help control aggression. Haldol is usually used to control tics and vocal utterances in Tourette’s syndrome and to treat schizophrenia. This medication decreases the neurotransmitter dopamine and may have other effects on the nervous system. Scientists do not yet fully understand how Haldol is able to reduce aggression in people with autism. Haldol can cause noticeable side effects including sleepiness and muscle stiffness.
Inderal propranolol hydrochloride Known as a beta-blocker, Inderal is used to treat hypertension (high blood pressure) and other heart-related conditions. Inderal is also used to help prevent migraine headaches in adults and children. Inderal is being studied as a treatment for severe aggression in children with autism. Inderal LA is a long-acting form of Inderal.
Klonopin clonazepam Clonazepam is indicated for use to treat seizure disorders and panic disorder. It may also be prescribed off-label for other conditions. Klonopin is one of a group of drugs called the benzodiazepines; it works by correcting imbalances in brain chemistry which may cause anxiety. Clonazepam may be habit-forming. Patients should not stop taking the drug suddenly before consulting a physician because the drug dose may need to be lowered slowly over time.
Invega paliperidone Paliperidone is indicated for treatment of schizophrenia in adults. It may be prescribed off-label for children with autism. Invega belongs to a class of drugs called atypical antipsychotics. Common side effects include dizziness, drowsiness, dry mouth, headache, lightheadedness, restlessness, and weight gain. More serious side effects can occur, and close communication with the physician that prescribed the medication is advised.
Lamictal lamotrigine Lamictal is an anticonvulsant and mood stabilizer that may be prescribed off-label for people with autism to help reduce lethargy (tiredness), irritability, hyperactivity. It may also improve language, communication, and social skills. Lamictal is indicated for treatment of epilepsy to help control seizures, and for bipolar disorder to delay mood swings. Lamictal seems to change how neurons turn on and off, which affects the release of glutamate and aspartate, two amino acids that are important in neuron signaling. There is a low risk of serious rash which can lead to death, so people taking this medication need to be monitored closely by a medical professional.
Luvox fluvoxamine maleate Luvox is an antidepressant that may be prescribed off-label for people with autism to help decrease repetitive movements and improve social contacts. It is used to treat obsessions and compulsions in people with obsessive compulsive disorder (OCD) who are at least 8 years old. This medication is a serotonin reuptake inhibitor (SSRI). One possible serious side effect of Luvox is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully against the clinical need for the drug. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Mycostatin
nystatin Oral medication is Nystatin; cream form is Mycostatin. Mycostatin and Nystatin are prescribed to treat fungal infections of the skin, mouth, vagina, and intestinal (digestive) tract.
Namenda memantine hydrochloride
Namenda is available as tablets or oral solution. It is indicated for treatment of moderate to severe Alzheimer’s dementia. Namenda may be prescribed off-label for people with autism in an effort to help improve language, social behavior, and other behaviors. Namenda is a glutamate receptor antagonist (inhibits glutamate binding to its receptors).
Paxil paroxetine Paroxetine is an antidepressant that is a type of selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a neurotransmitter in the brain, which helps to improve certain mood problems. Paxil® is prescribed for depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder, and premenstrual dysphoric disorder. It may also be prescribed for people with autism. One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Pepcid famotidine Pepcid is a type of histamine-2 blockers that decreases the amount of acid that the stomach produces. Pepcid® is used to treat and prevent ulcers in the stomach and intestines. It also treats other conditions in which the acid produced by the stomach is a problem, such as gastroesophageal reflux disease (GERD) and heartburn.
Provigil modafinil Provigil promotes wakefulness. The FDA approved modafinil to treat narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Off-label, modafinil is used by sleep deprived people to stay awake and to treat fatigue, depression, multiple sclerosis and Attention-Deficit/Hyperactivity Disorder (ADHD). The FDA rejected an application by the manufacturer to use modafinil as an ADHD drug due to the side effect of serious rashes. Modafinil is not approved for use in children under the age of 17. Side effects may include serious rash, chest pain, anxiety, stuffy nose, diarrhea, back pain, sleepiness and nausea or upset stomach.
Prozac fluoxetine hydrochloride
Prozac is an antidepressant that may be prescribed for people with autism to help decrease aggression and depression. It can also help reduce repetitive behaviors, and improve language and social interactions. In some individuals, Prozac can make these symptoms worse, so each individual must be monitored closely. Prozac® is indicated for depression, obsessive-compulsive disorder, bulimia nervosa, and panic disorder in children and adults. This medication is a serotonin reuptake inhibitor (SSRI). One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Remeron mirtazapine Mirtazapine is an antidepressant that adjusts the balance of neurotransmitters like norepinephrine and serotonin in the brain. Remeron® belongs to a class of drugs called tricyclic antidepressants and is chemically different from serotonin reuptake inhibitors and MAOs. It is FDA-approved for use in treating major depression in adults. Mirtazapine may also be prescribed off-label for children with autism. Side-effects include abnormal dreams and thinking, constipation, dizziness, dry mouth, flu-like symptoms, increased appetite, sleepiness, weakness, and weight gain. In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of mirtazapine or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Revia - Vivitrol
naltrexone
This medication may be prescribed for autistic children to help improve ability to socialize and make eye contact, and also to help reduce pain sensitivity, self-injury behaviors, and repetitive behaviors. Revia is indicated for people who are trying to stop an addiction to alcohol or opioids (e.g., morphine or heroin). This drug is an opioid antagonist, so it binds to opioid receptors and blocks the binding of alcohol or other drugs to the receptors, thus blocking the opiates from having an effect so the person will stop their addiction. Some children with autism have higher than normal levels of beta-endorphins in their nervous system, and naltrexone can lower beta-endorphin levels. An extended release injectable form is also available and is called Vivitrol.
Risperdal risperidone Available as tablets, oral solution, or orally-disintegrating tablets, this psychotropic medication is used to treat: 1) aggression, irritability, and severe behavior problems in autistic children 5-16 years old; 2) bipolar mania in individuals 10 years old and up; and 3) schizophrenia in adolescents and adults. Side effects might include weight gain, increased appetite, and sleepy or groggy feelings. Risperdal Consta, an injectable form of risperidone, is usually used to treat schizophrenia in adults.
Ritalin - Methylin
methylphenidate hydrochloride Ritalin, Ritalin LA, Methylin Oral, or Methylin are mild central nervous system stimulants that may be prescribed for people with autism to help reduce hyperactivity and repetitive movements. Methylphenidate is indicated for treatment of attention deficit disorder (ADD), attention-deficit/hyperactivity disorder (ADHD), and narcolepsy (falling asleep at the wrong times).
Rozerem ramelteon Ramelteon is an oral medication (tablets) for treatment of insomnia (an inability to sleep well). Ramelteon stimulates melatonin receptors in the nervous system, thereby promoting sleepiness. Many children with autism have problems sleeping and ramelteon is currently being tested for effectiveness in children with autism.
Sarafem fluoxetine hydrochloride Sarafem is an antidepressant that may be prescribed for people with autism to help decrease aggression and depression. It can also help reduce repetitive behaviors, and improve language and social interactions. Sarafem is indicated for premenstrual dysphoric disorder (PMDD), a syndrome associated with menstruation in adult women. This medication is a serotonin reuptake inhibitor. One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Sporanox itraconazole Sporanox is prescribed to treat serious fungal infections which may invade any part of the body including mouth, throat, lungs, or nails.
Stablon - Coaxil - Tatinol
tianeptine Other trade names are Coaxil (Europe) and Tatinol (Asia and Latin America). Drug currently approved for use in France that is an antidepressant. Tianeptine is a serotonin reuptake enhancer. This mechanism of action differs from many antidepressants that are serotonin reuptake inhibitors. Tianeptine has also been used to treat asthma in children, erectile dysfunction in men, and Attention Deficit Hyperactivity Disorder (ADHD).
Strattera atomoxetine hydrochloride Strattera may be prescribed off-label for people with autism to help with hyperactivity, obsessions, and other behavior problems. Strattera is usually prescribed for the treatment of attention-deficit/hyperactivity disorder (ADHD). Strattera works by changing the ways some neurons are turned on and off. One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Symbyax fluoxetine hydrochloride and olanzapine Medication containing a combination of fluoxetine and olanzapine. Symbyax is indicated for treatment of depression in bipolar disorder. Symbyax contains an antidepressant (fluoxetine) and an antipsychotic (olanzapine). Symbyax may be prescribed for people with autism to decrease anger, aggression, and repetitive movements; and to improve social interactions.
Tenex - Intuniv guanfacine Tenex or Intuniv (extended release form) stimulates certain receptors in the brain and nervous system. Guanfacine is indicated for lowering blood pressure and improving attention in attention-deficit hyperactivity disorder (ADHD). Guanfacine may also be prescribed off-label for sleep disorders, post-traumatic stress disorder, anti-social behaviors, oppositional disorder, and Tourette’s disorder. 
Thorazine - Thorazine Spansule chlorpromazine Thorazine Spansule is the name for the sustained-release form. Chlorpromazine is available in tablet or injection form, and as suppositories. In children 1-12 years old, Thorazine may be prescribed for the treatment of severe behavioral problems such as combativeness and/or explosive hyperexcitable behavior. It is also prescribed for short-term treatment of hyperactive children who show excessive motor activity and conduct disorders that may include impulsivity, difficulty sustaining attention, aggressiveness, mood swings, and poor frustration tolerance. Thorazine is approved for the treatment of a number of other different conditions, including schizophrenia, severe nausea and vomiting, manic type of manic-depressive disorder.
Tofranil imipramine hydrochloride Tofranil is a tricyclic antidepressant that is usually prescribed for depression, and for childhood enuresis (bed-wetting). One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Topamax topiramate Topamax is an anticonvulsant that may be prescribed for people with autism to help reduce irritability and self-injuring behaviors. Topamax can also help reduce seizures. Topamax is indicated for reducing seizures in people with epilepsy for ages 2 years old and up; and also for preventing migraine headaches. Topamax is available as tablets and as sprinkle capsules that can be taken as a whole capsule or sprinkled on food. This medication may have a side effect of metabolic acidosis (the blood getting too acidic). People taking this medication need to be monitored closely by a medical professional and may require regular blood tests.
Trileptal oxcarbazepine This anti-seizure medication affects the way neurons are turned on and off. People with autism who also have seizures might be prescribed this medication. Anti-seizure medicines may not completely eliminate seizures but might reduce the number of seizures. Doses and blood levels of this medication often need to be watched closely by a doctor or other health care professional.
Valium - Diastat
diazepam Valium is a sedative that may be prescribed for people with autism to help reduce aggression and anxiety, or for seizures. It also comes as Valium Injection, or Diastat, a rectal gel form. The response to diazepam can vary between individuals with autism, so each individual should be monitored carefully. Diazepam is indicated for anxiety disorders, alcohol withdrawal, skeletal muscle spasms, and as supplemental medication for severe seizure disorders.
Versenate edetate calcium disodium Versenate chelates or strongly binds to divalent and trivalent metals including lead, zinc, cadmium, manganese, iron, and mercury. Versenate is usually prescribed for metal poisoning, particularly lead. Versenate may be used in children with autism to reduce heavy metals in their body in an effort to improve behaviors. While Versenate may be prescribed for children, serious side effects (including death) can occur as a result of Versenate therapy. Versenate has been confused with Endrate (edentate disodium), which is usually administered only to adults under emergency circumstances because of the risk of death. Endrate should not be used in children, according to the FDA and the CDC. Any chelation therapy in children should be administered under careful medical supervision.
Xanax alprazolam Alprazolam is one of a type of medications called benzodiazepines. It works by helping restore chemical balance in the brain when there are imbalances that may cause anxiety. Alprazolam is typically used to treat anxiety disorders, panic disorders, and anxiety caused by depression. It may also be prescribed off-label for people with autism. Caution: alprazolam may be habit-forming and should be used only by the person it was prescribed for. Alprazolam should never be shared with another person, especially someone who has a history of drug abuse or addiction. The medication should be kept in a secure place where others cannot get to it.
Zoloft sertraline hydrochloride Zoloft is an antidepressant that may be prescribed to help reduce anxiety and repetitive behaviors in people with autism. Zoloft is indicated for major depressive disorder, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder. This medication is a serotonin reuptake inhibitor (SSRI). One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.
Zyprexa olanzapine
Zyprexa is a psychotropic medication that may be prescribed off-label for people with autism to reduce disruptive and repetitive behaviors. Zyprexa® is indicated for treatment of schizophrenia and bipolar disorder (mania). Zyprexa Intramuscular is indicated for the treatment of agitation in people with schizophrenia and bipolar mania. Zyprexa works as a dopamine and serotonin type 2 antagonist, and has other effects on the nervous system. Side effects can include weight gain, increased appetite, and dry mouth. Other forms of this medication are called Zyprexa Zydis, or Zyprexa Intramuscular.

 

Epilepsy & Behavior, by Hughes, JR, published in 2008, summarized Oct 28, 2008

Children with autism have medical and therapy costs that are $4,110-6,200 more than children without autism.

This article reviews the autism research studies that were published in 2007. The most common drug therapy is risperidone, which may lessen irritability, repetition, and social withdrawal. Other drugs used as autism therapy include atypical antipsychotics, antibiotics, and memantine. One study found that acupuncture helped over half of the children with autism who received treatment. The article also reviewed massage therapy, robots, electroconvulsive therapy, hyperbaric oxygen therapy (HBOT), and music therapy.


Medical Hypotheses, by Bransfield, RC, Wulfman JS, Harvey WT, and Asman AI, published in 2008, summarized May 23, 2008

Antibiotics that treat Lyme disease may help some people with autism.

This article was written to describe the possibility that autism is made worse by Lyme disease. Many doctors and parents have noticed that mothers who had Lyme disease were more likely to give birth to children with autism. Also many adults who get Lyme disease have symptoms that are like autism. The authors believe that 20-30% of autism may be caused by the bacteria that cause Lyme disease. They believe that another infectious agent (Mycoplasma) may be a factor in 58% of cases of autism.


Medical Hypotheses, by Finegold, SM, published in 2008, summarized Apr 4, 2008

Vancomycin therapy may help autism by killing clostridia bacteria.

In this review article, the author looks at published research that supports the idea that autism may be caused by a bacterial (clostridia) infection of the gut. The author states that in most cases autism begins after the child receives antibiotics, thus making it possible for bad bacteria to grow up in the gut. The author believes that the widespread use of antibiotics may be the cause of the increase in autism. In many cases, autism improves when the child is given the drug vancomycin, which kills any bad bacteria in the gut. The bad bacteria have spores, however, and the spores survive treatment with vancomycin and are able to cause a relapse of autism.


Medical Hypotheses, by Boorom, KF, published in 2007, summarized Aug 10, 2007

Broad spectrum antibiotics that also work against protozoa may be a good treatment for autism.

The author notes that in the 1990s an increased number of people were diagnosed with autism and inflammatory bowel disease (IBD). He suggests that autism may be caused by a new form of a type of bacteria (Blastocystis) that is found in the gut. The first step to see if this is true would be to screen people with autism to see if they have antibodies to this type of bacteria. This type of bacteria is now difficult to identify in the gut. He suggests that it would be easy to develop a routine test for it in the future.


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School Lunches for Kids with ASD

Sep 11, 2008 by Anonymous

SCHOOL LUNCHES FOR KIDS WITH ASD: DELICIOUS, HEALTHY & POSSIBLE.

THE CHALLENGE:

With only twenty minutes to eat, kids with autism spectrum disorder (ASD) should have "fast" foods that are healthy, tasty, loaded with nutrients and free of the culprits that are common problems: gluten, milk products, soy, and artificial additives and coloring. Add to the list sensory issues involving food texture, color and taste along with unusually picky appetites so common in ASD - and the task seems insurmountable. Beyond the challenges with foods are the safety issues of the food containers themselves, especially plastics containing phthalates and bisphenyl A (BPA). And of course there is the "cool" factor which affects pre-school through high school. Food that is different is totally uncool for kids who already face so many social and learning stigmas.

Knowing the challenges, we can now focus on the solutions.

THE SOLUTIONS:

Basics

As is the case with any meal, there are some basics to follow. Blood sugar control is critical. All people are affected by rapidly rising blood sugar which then cascades down too quickly and too low. The most noticeable effects are on brain function especially mood and attention. As the blood sugar drops too quickly, there can be irritability, hunger headaches, lack of focus, behavior problems, and cravings for a "quick sugar fix" which keeps the cycle going. This interferes with learning and can be disruptive to the class. Protein and fiber stabilize blood sugars. Below is a summary of the basic rules for any meal including school lunch.

Assumptions

All food suggestions are GFCF (gluten-free, casein-free). Glutens include wheat, oat, barley, rye, spelt and kamut. Milk products and milk casein include milk, yogurt, cheese, creams, ice cream, cream sauces, and butter.

Avoids

Glycemic foods which raise blood sugar (glucose) quickly include: sugars, sodas of any kind, candy, sweets, juices, and any refined grains (pretzels, bread, crackers, bagels, chips) on an empty stomach. Limit the sugars and keep the refined carbohydrates limited. If small amounts are consumed at the end of the meal, the negative effect is less.

A word on sodas - both regular and diet. They have no place in a healthy diet. They are high in phosphorus which depletes healthy nutrients. Consider them removers of electrolytes, not drink options. Water is best, but other good choices include: dilute juices, seltzer water with juice to flavor, vegetable juices (V8)

Promote Protein at every meal or snack

Choices include fish, poultry, meat, eggs, beans, nuts and seeds.

Avoids: milk products

The serving size for protein for each person is the size of the palm. A child's may be 1 to 2 ounces of meat/chicken/fish and a teen and adult may be 3 to 5 ounces. See the chart for guidelines

For beans, the serving size is two cupped palms full. See the chart for guidelines.

Fabulous Fiber at every meal

Choices include fruits, beans, nuts, seeds and grains.

Avoid: glutens

If your child eats very few vegetables, fruits, grains, nuts, seeds and beans, added fiber is important. Fiber as pure guar gum is easy to add to any recipe and also to drinks. It is GFCF and more fine than sugar, mixing completely in water or juice. See the table for fiber intake suggestions.

Favorite Foods at every meal or snack

Include at least one food that is a favorite in order to promote more interest in the meal.

Fun Meals - Part of the Cool Factor

Take a tip from the fast food marketers and include a surprise gift in the lunch. It might be a small collectible such as cars, baseball cards, characters, hair clips, stickers, or child's ring or bracelet. Home made "giftlets" (tiny gifts) are perfect.

Guidelines and Ideas

Go organic as much as possible. "USDA Organic" means the food is produced without the use of harmful pesticides, artificial fertilizers, antibiotics, growth hormones human waste, or sewage sludge, and that they were processed without ionizing radiation or food additives. Children with ASD are already coping with their own excess metabolites and really can not handle the burden of harmful chemicals in the environment and foods. The less the exposure the better. Anything you can do for your child is a benefit.

There are numerous resources for GFCF foods and recipes online and in many books. Utilize all of these to find the commercially available foods your child will eat as well as recipes that are not just GFCF, they are nutritious and delicious. Test them at home - not in the school lunch. There are GFCF juice boxes, pretzels, breads, wraps and snacks.

Establish three to five basic lunches that work. If your child is willing and interested, engage him or her in the process. Test new foods out at home until you have the food right and the combination of foods right.

Use freezer packs for keeping foods cold and thermos for hot foods. Include non-toxic hand sanitizers which are commercially available (avoid the commercial sanitizers). You can also send two paper towel pieces - one moistened with soap and one moistened with water..

Packaging - a good opportunity to Go Green!

Again - go with the marketers - jazz it up! Select a lunch container your child loves. Young children love to decorate a lunch box with stickers and paints. Make the lunch box the child's own work of art personalized with a name. Reusable containers and boxes are the green way to go. Older children will definitely want to select whatever is considered cool. The most cool may be a paper bag or small recycled bag carried in a back pack. Go with the trend and your child's own choice. There are companies who make safe, BPA-Free, safe lunch box sets with inserts for the different foods.

To avoid plastic wraps for sandwiches, use wax paper or parchment paper. Avoid containers with BPA by avoiding items with the recycle number 7. There are many BPA -Free containers which can be washed and reused. Your child will need to know to bring these back home rather than throw them away.

For napkins, use washable cloth napkins or dishcloths, or choose processed chlorine-free (PCF), post-consumer-waste (PCW) paper napkins available in stores and on line. If utensils are needed, use stainless steel appropriate to the child's skill level and age.

Nutritious Can Be Delicious - Even for the Picky Eater - The Trojan Horse Technique

Remember Odysseus from seventh grade mythology? Seeking to gain entrance into Troy, he cleverly ordered a hollow wooden horse so large that the Greek army could hide inside. What looked like a huge horse was really a disguise to conquer the city. We have used this concept for decades to hide nutritious food to nourish picky eaters.

Rather than introduce a new food in its natural form, begin by hiding a very small amount (about a tablespoon) of it as puree mixed or blended into a well-liked and well-tolerated food. This approach allows the body to accept the new food. As the child accepts the taste, include more. Children who have food texture issues are especially good candidates for blended foods because their sensory development may be younger than their chronological age. Adapt to the sensory level and return to purees until sensory issues improve. Rather than focusing on getting a child to tolerate foods that he perceives as "lumpy" or unpleasant to chew, the goal is getting a child to eat nutritious food, however you can.

Match the Color and Texture

Assume the new food is a vegetable, use organic baby food purees or make your own. Puree the new food into an established food that does not change the overall color, texture, smell, or taste. If a child eats nothing but white food, start with very light-colored vegetables including squash, cauliflower and corn. If the child likes ketchup or tomato sauce, then introduce deeper-colored vegetables such as beets, greens, peas and beans. Pureed vegetables can be beaten into batter for pancakes, muffins, brownies, and cookies or into tomato and other pasta and pizza sauces, and even into ketchup.

Mix Fruits and Vegetables

Vegetable juice makes a healthy addition to fruit juice. Try mixing carrot juice with orange juice, and then adding a teaspoon or so of another vegetable juice. Serve in a brightly colored sippy cup to camouflage any color changes. Blend pureed vegetables into cooked fruits such as applesauce or pearsauce, into meatballs, and even into nut butters. Expand ideas as tolerance improves. Be sure to carry out the Trojan Horse technique out of the sight of your child!

Muffin Casseroles

Many families have developed what we call muffin casseroles. One resourceful mother developed a GF/CF muffin for her child who ate only breads and muffins, and then gradually added fruit puree to the batter. As he tolerated fruits, she moved to vegetable purees, and finally added pureed meat. Until he was able to transition to eating foods in a traditional manner, he ate his muffin casseroles at every meal and snack-and loved them!

Increase Protein

The Trojan Horse technique is especially useful for kids who need more protein in their diets. Add eggs, especially the high-protein whites, and rice-protein powders to batters, breads, smoothies, meat sauces and meatballs. Do not add raw eggs to smoothies.

Gradually Move On

AS your child expands to eating vegetables, try vegetables dipped in honey or mayo/ketchup mix or hommus. It is a start . As a child accepts an increasing number of foods presented in a sneaky manner, eventually, he/she will accept the food alone - we promise! All it takes is patience, and a lesson from Greek mythology!

Choose one from each section. This list is GFCF. Also avoid any foods which provoke reactions or those forbidden at school (nuts for examples) or foods The "Other" section is optional.

Some Protein Choices: chicken strips, GFCF chicken nuggets w/ketchup to dip, meat slices rolled up, shrimp (send frozen, will thaw by lunch) w/seafood sauce to dip, organic "deli" chicken slices, hommus plain, on bread or crackers or as dip for veggies, muffin "pot pies", soy yogurt, egg salad, hard boiled eggs or deviled eggs, peanut butter on crackers or apples, nuts - all varieties - almonds, cashews, pecans, pistachios, hazelnuts. Hot food for thermos: chili or soups, turkey hot dogs cut up, GFCF pizza.

Some Vegetables & Fruit Choices: These can be eaten plain or dipped in GFCF sauces, ketchup or honey. Foods include: cup of vegetables, baby carrots or carrot strips, broccoli "trees", apples, bananas, berries, oranges, peaches, grapes, pineapple, melon, natural fruit cocktail in natural juice, raisins, apricots,  applesauce in cups, any blended fruit sauce.

Drink Choices: water, fruit juice, V8, V8+fruit, seltzer w/juice, fruit smoothie, other milk (soy, rice, coconut, almond), and keep drinks partially frozen so they will remain cold. 
Other: GFCF pretzels, rice crackers, baked tortilla chips, GFCF dry cereal, GFCF vegetable gummies, small GFCF cookie.

The above is an excerpt from the book The Kid-Friendly ADHD & Autism Cookbook: The Ultimate Guide to the Gluten-Free, Casein-Free Diet
by Pamela J. Compart, M.D. and Dana Laake, R.D.H., M.S., L.D.N.
Published by Fair Winds Press; November 2006;$24.95US/$32.50CAN; 978-1-59233-223-6
Copyright © 2008 Pamela J. Compart, M.D. and Dana Laake, R.D.H., M.S., L.D.N

Author Bio
Pamela J. Compart, M.D., is a developmental pediatrician in Columbia, Maryland. She combines traditional and complementary medicine approaches to the treatment of ADHD, autism, and other behavioral and developmental disorders. She is also the director of HeartLight Healing Arts, a multidisciplinary integrated holistic health care practice, providing services for children, adults, and families.

Dana Godbout Laake, R.D.H., M.S., L.D.N., is a licensed nutritionist in Kensington, Maryland. Within her practice, Dana Laake Nutrition, she provides preventive and therapeutic medical nutrition services. Her practice includes nutritional evaluation and treatment of the full spectrum of health issues affecting adults and children with special needs.


Have you seen this video by a Doctor in England that has a book out now on how she cured her son's severe autism with a special diet and probiotics. She says that one of the main causes of autism is taking antibiotics and that one needs to replace the good bacteria in the digestive system in order to heal the digestive system and that will cure the autism. Here the free you tube video
http://www.youtube.com/watch?v=Zpe4kcvaesw
http://www.amazon.co.uk/Gut-Psychology-Syndrome-Depression-Schizophrenia/dp/0954852001


The Best Christmas Pageant Ever

Dec 21, 2006 by Anonymous

You’re not going to believe this, but the kids are sick AGAIN! Just in time for Christmas, as I had feared. They’ve both got colds and upper-respiratory clogging. Such fun! I can’t believe our bad luck with the holidays this year. Stomach flu on Halloween, pink-eye on Thanksgiving and now colds. I had both Thomas and Hayley at the doctor today, got an antibiotic and cough suppressant, so hopefully they’ll be in better shape by the time Santa slides down the chimney Sunday night.

Thomas’ Christmas show on Tuesday was so much fun! (I’m glad he was able to participate; the show had just ended when I noticed Thomas’ runny nose.) He was very well-behaved, sitting with his class on the mat in the gym until it was their turn to sing. He even wore the little reindeer antlers the kids made with brown construction paper and cut-outs of their handprints! He sang when it was their turn to sing and when it was over, Hayley and I came to sit on the mat with his classmates and ate “reindeer food.” It was so much fun and Thomas was better behaved than Hayley, really. That seems to be a theme lately. I’m sure it has to do with her age, being two-and-a-half. She was much more upset at the doctor today than Thomas was, but he gave Hayley a hug after the doctor was finished looking at her and said, “It’s okay, Hayley.” It was very sweet.

Thomas had mostly good days at school leading up to Winter break. He’s been participating more actively in class, coming up with their “message of the day” and telling his teacher what the weather is like outside. His teacher hasn’t mentioned any problems with the new kids who’ve been in class, so maybe he’s more accustomed to that kind of thing now. One of the teacher’s aides told me yesterday that Thomas likes to play a lot with one of the new girls in his class.

This is going to be shorter tonight, as I still have important business to finish up tonight. I don’t anticipate writing again until after Christmas (the day after Christmas, the kids have a regular check-up appointment with their pediatrician, with shots, so I’m sure I’ll have something to say), so Happy Holidays to everyone!


The Sound of Mucous

Nov 21, 2006 by Anonymous

We’re all sick. And I think Thomas has pink-eye.

Even as I sit here typing, I am painfully aware of all of the germs and wee creepy-crawlies that are most likely throwing rowdy parties all over the keyboard. When will all the sickness end? At least the kids won’t get the flu…or at least they won’t get whatever strain of the flu the CDC deems most threatening this season! I’m still sick and Jonathan is sick now, too. Just in time for Thanksgiving! Thomas missed the Halloween parade, and now he can’t go to school tomorrow when the class would surely be making cute little hand-turkeys.

Of course, since Thomas most likely has conjunctivitis, I will have to take him to the doctor tomorrow…all by myself. Even going to the doctor is not what worries me so much – it’s the eye drops we will have to administer if he’s got pink-eye. How in the world am I going to give Thomas eye drops? Even I, a neurologically-typical grown-up adult cannot stand eye drops. The antibiotics around Halloween was one thing…I could mix that into a cup of juice! I am already sweating at the thought of having to hold him down and get drops in his eyes. Would it be considered child abuse to hog-tie him to administer ocular antibiotics? Honestly, I don’t see it (no pun intended) happening any other way. At least, at least he will be okay to go back to school on Monday if we get him on the antibiotics tomorrow. Even twenty-four hours on the meds should make him okay for Thanksgiving. I should probably just have the pediatrician write a prescription for all of us, since I cannot fathom that just Thomas would get pink-eye. I know how contagious it is.

And the hits just keep on comin’.

Okay, enough of my pink-eye rant. Back to Thomas. The potty training is still going well…he usually has one accident every day or every other day. Getting him to listen to his body’s cues continues to be a struggle, but if we’re diligent about taking him to the bathroom, accidents can be avoided. At least we’re only buying diapers for one child now.

Thomas continues to enjoy singing! He was singing “Jingle Bells” today, and I’m not really sure where he picked it up. We haven’t sung it yet this season, but the morning bus driver was playing Christmas music this past week, so maybe that’s where he heard it. He really seems to like singing and even Hayley is picking up on it. She’s started asking Thomas to sing, too.

One of the greatest things he’s doing is answering when we call his name! We find this so encouraging and we know that he’s listening to us. Lots of times now, I’ll say, “Thomas?” and he’ll respond, “Yeah?” Then I ask him what he’s doing. He’ll say, “Oh, I’m um…just jumping on the couch.” He’ll ask me what I’m doing, too. We have these little conversations now! It’s so much fun and it catches me off-guard a lot of the time. Sometimes he’ll ask me a question and it’s so novel and strange to me that Thomas would ask me something that I have to take a minute to process that he’s waiting for a response. And after I respond sometimes, he’ll say, “Oh. Okay.” So cool!

Unfortunately, Thomas has been pretty rough with Hayley lately. Just tonight they were “playing” while I was putting away some laundry. I heard them laughing and carrying-on, when all of a sudden Hayley’s laughter turned to shrieks of pain. I went into Thomas’ room, soothed Hayley who said, “Thomas hurt it,” and went back to my laundry after a stern admonishment about not playing too rough. Five – no, one minute later, the same thing happened again. Thomas came running out of his room looking sheepish and Hayley was laying on the floor weeping. I had had enough. Jonathan was sick on the couch and all I wanted to do was put away some clean clothes, but no! Getting laundry done was just too much to ask. I was seriously thinking about taking the old baby-backpack out of storage and just carrying Hayley around papoose-style until she’s fourteen and better able to defend herself. I try to explain to Thomas that Hayley is too little for playing rough and he’s got to be more careful. The thing is that he knows when he’s hurt Hayley. He does understand that if she’s crying, she’s upset about something and he usually knows that he hurt her. Is this just brother-and-sister stuff, or is it happening because Thomas can’t understand when he crosses the line? I might be better off telling Hayley that when Thomas is playing too rough, she needs to come to me. The thing is that when Hayley is hurt, she just lays there like a lump until somebody comes to save her. A little more initiative on her part would help the matter greatly, I think.

So we’re off to the doctor tomorrow and my mother-in-law’s house on Thanksgiving, if we’re given clearance from the pediatrician. (Even if we’re not, I’m sure we’ll still go and issue the firm edict that nobody is to touch Thomas – or really any of us – without signing a waiver.) I’ll probably bring my antibacterial wipes and Lysol and wear them around my waist in a holster-type apparatus. Nothing says “Thanksgiving” like following your kids around all day, spraying and wiping down everything they touch. I’m banking on a goofy skin condition for Christmas that will have us up to our elbows in lotions and creams.

Happy Thanksgiving!



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  • Synonyms for antibiotics include: antibiotic
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