Autism Therapy: deletion

definition of deletion: not yet defined.

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Intranasal Insulin to Improve the Developmental Delay in Children with 22q13 Deletion Syndrome: An Exploratory Clinical Trial
Journal of Medical Genetics, by Schmidt, H., Kern W., Giese R., Hallschmid M., and Enders A., published in 2009, summarized May 5, 2009

Intranasal insulin may help some children with autism move better and gain IQ points.

This study was designed to see if squirting insulin into the nose (intranasal) of children with a type of autism (Phelan-McDermid syndrome) would help with the symptoms of autism. The trial involved six children who were treated with intranasal insulin for up to one year. The children were different ages (9 months to 6.5 years) and had different symptoms of the syndrome. Patient three was the least impaired patient (age 3) and she was the only one who had a bad response to the treatment. The authors do not know why the intranasal insulin helped the children.


Co-Occurrence of ADHD and Autism Spectrum Disorders: Phenomenology and Treatment
Expert Rev Neurotherapeutics, by Reiersen, AM, and Todd RD, published in 2008, summarized Jun 2, 2008

Methylphenidate (Ritalin) may help children who have both autism and attention deficit hyperactivity disorder (ADHD).

Children with autism and ADHD can be hard to treat. This review article describes the few research studies that look at treatments for children with both ADHD and autism. In most cases, standard ADHD drugs (methylphenidate and atomoxetine) are used to treat children with autism and ADHD symptoms. One study looked at autism and ADHD and found that methylphenidate did help children with both autism and ADHD. Children with the 22q11 deletion genetic syndrome may have both ADHD and autism and they can also be treated with methylphenidate.


A Review of Neurocognitive and Behavioral Profiles Associated with 22q11 Deletion Syndrome: Implications for Clinical Evaluation and Treatment
Current Psychiatry Reports, by Ousley, O., Rocker K., Dell ML, Coleman K., and Cubells JF, published in 2007, summarized May 17, 2007

Children born missing a certain group of genes are said to have 22q11 deletion syndrome (22q11DS). This review article describes how these children are at risk for autism and what can be done to help them. About 50% of children with 22q11DS are either autistic, have Asperger's syndrome, or have pervasive developmental disorder-not otherwise specified (PDD-NOS). Often parents start to worry about their child's lack of language and poor social behavior before the age 2. Parents may also note that the children have trouble making and keeping friends in school. The authors report that treatment options include speech/language therapy, applied behavioral analysis (ABA), social skill training, structured work with friends, help with school work, and drug therapy.


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Responding to neurofeedback

Feb 1, 2011 by Anonymous

I used neurofeedback for my daughter for about a year, when she was 14. She was gong though a lot of changes at the time, very anxious. She also has other disabilities a deletion of the short arm of chromosome 4, celebral palsy and has had a stroke she walks with a limp after intensive therapy for many years. We used Conductive Education, a Hungarian technique for children with motor disorders.

The results of NFB were-she was more verbal after NFB and surprisingly her balance, gait and ability to move around improved noticeably. She also had noticeable changes in cognitive behaviour and ability to communicate.

Unfortunately she decided she no longer wanted to stay hooked up to the electrodes and TV and we had to abandon the treatment. We are using acupuncture at present, along with Neurolink, massage and homeopathy. She is now aged 20 years.


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