Autism Therapy: diabetes

definition of diabetes: not yet defined.

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Journal of Medicinal Food, by Kaur, IP, Kuhad A., Garg A., and Chopra K., published in 2009, summarized Aug 13, 2009

Probiotics may be helpful for digestive problems that can occur in some children with autism.

Probiotic therapy involves taking supplements or foods that contain "good bacteria" that live and thrive in a healthy gut. The two most common good bacteria are Lactobacillus and Bifidobacterium. This review article describes how some people do not have enough good bacteria in their guts and may be helped by probiotic therapy. People with autism who also have gut problems (gas, bloating, diarrhea, inflammatory bowel disease) may find probiotic therapy very helpful. Probiotics may also be helpful for a broad range of health issues, such as diabetes, obesity, and allergies.


US Pharm, by Tahir, R., published in 2007, summarized Oct 7, 2008

Patients on atypical antipsychotics such as risperidone should be tested for weight gain, diabetes, and problems with cholesterol.

Atypical antipsychotics are sometimes used to treat behavior issues in children with autism. This class of drugs (atypical antipsychotics) started being used in the 1990s. Doctors still do not know for certain how atypical antipsychotics work. This review article describes the effects of a type of drug therapy (atypical antipsychotics) on energy (metabolism) in the body. Many atypical antipsychotics bring with them the risk of weight gain and metabolic problems.


J Appl Behav Anal, by Shabani, DB, and Fisher WW, published in 2006, summarized Mar 25, 2008

Behavioral therapy was used successfully to teach a boy who was intensely afraid of needles to remain calm while his blood was drawn from his arm.

An 18-year-old boy with autism, mental retardation, no vocal speech, and Type 2 diabetes had been so afraid of needles that he had not allowed anyone to draw blood for over 2 years. He was said to have a phobia, or intense fear, of needles. Gradually, the medical staff taught him to position his arm on the table. Then they approached him with a needle, moving gradually closer with the needle over several attempts. When he did not pull his arm away, he was given a reward of cookies. After 31 attempts, he allowed the blood draw from his arm. He continued to allow blood draws for most attempts after the first success. The authors concluded that methods to treat phobias can be successful with people with severe disabilities including severe autism.


Pediatric Drugs, by Chavez, B., Chavez-Brown M., Sopko MA, and Rey JA, published in 2007, summarized Oct 17, 2007

Several drugs can be used to help with symptoms of autism: risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole, or clozapine.

This review article describes the use of drug therapy (atypical antipsychotics) to treat autism. Drug therapy can be used to control symptoms of aggression, irritability, and hyperactivity. Of all the drugs used to treat autism, risperidone is the one that has been tested the most in research studies. Risperidone and other drugs like it can help symptoms of autism, but they can also cause weight gain. These types of drugs may also increase the risk for diabetes.


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And the hits just keep on comin'

Jan 25, 2007 by Anonymous

My trip to Denver is now behind me and I can happily report that everything went well while I was away. The only casualty was one lost shoe, which I found roughly five minutes after returning home. It was behind the treadmill, which leads me to an amusing story about my husband and how after nine years of marriage, I still don't know him as well as I thought I did.

When Jonathan was diagnosed with diabetes last July, he saw his doctor who recommended a diet and exercise regimen. Jonathan faithfully stuck to the diet and has lost over seventy pounds as a result, which is great. For my part, I decided that we should move the treadmill back into the house (which is as difficult as jogging three miles on the machine) so that he could do the exercise part. Unfortunately the treadmill has been used as a clothes hanger since then. Until Saturday, Jonathan decided, while I was away and couldn't be there to keep the kids out of his way, that he would use the treadmill. I cannot fathom what drove him to it. I simply don't understand what came over him. "Okay, well, that's great," is what I said to him, while on the inside I thought "????!!." He complained that Thomas was putting his cars on the belt and watching them scoot off the end of the machine while Jonathan was trying to use it. I'm not sure what he expected Thomas to do when tempted with a little car converyor belt, but there it is. Somehow, Thomas' left shoe got wedged behind the treadmill after Jonathan used it and it delayed their arrival at the airport to pick me up on Sunday night. As I said, I found it promptly after returning home and all was right with the world.

Until Monday morning, when Hayley was peeling up linoleum tiles in the kitchen with very little effort, exposing the concrete slab underneath. "Okay! That's it!" I declared and put in a call to our favorite flooring installer. As I have mentioned in previous blogs, our carpeting has been a germ virus and bacteria farm ever since we brought Sophie (our Springer Spaniel)  home five years ago. Neighborhood high school biology students wanted samples of it to put on slides in class. It got uglier as the years (and kids) wore on so replacing the flooring in the kitchen and living area has always been something we wanted to do. The trouble with the tiles in the kitchen finally lit a fire and I made inquiries.

Today, two nice young men spent nine hours in our home getting rid of the old and installing the new. Initially I would say that Thomas likes it, because when he walks now, the echo off the wood liminate and vaulted ceilings really gives his voice that extra "oomph" he's been looking for. Jonathan and I really enjoyed the squealing contests between Thomas and Hayley this afternoon. Also their little bare feet make a lot more noise slappign on the floor now.

We will see how Thomas does with it. I read a book of memories not long ago in which the autistic son would not put up with any environmental changes of any kind. His mother bought a new comforter for her bed and drew him pictures and really prepared her son for the change. The comforter had been on the bed for about two hours before the young boy removed it from his mother's bed and attempted to deposit it in a neighbor's recycling bin. Luckily, there is no way that Thomas could remove the flooring. Instead, he will probably make known his dislike of the situation in much more subtle ways. Unfortunately, I have no idea how he did in school today because his teacher sent home another little boy's artwork and daily report in Thomas' backpack. (A very understandable lapse . . . I could never handle her job on my best days.) The filthy old carpet was being cut up and removed as I walked Thomas out to the bus, so the change had already begun by the time he left. Also, he did go to bed better tonight than he did last night, but still not great. We're still dealing with these bedtime problems, but as long as we keep making changes, we'll have to expect difficult behavior to some degree. I really hope that we can get everything ironed out by the time we leave for our cruise.

Another fun thing . . . my doctor believes I am having anxiety problems. I see him on Saturday.

And the hits just keep on comin'. 


Essential Fatty Acids

Sep 24, 2006 by Anonymous

Essential Fatty Acids

I could go on and on about essential fatty acids (EFAs). They are important. They are found in breast milk. Only recently are they being put in formula and only in the more expensive lipil formula. They are similar to the cod liver oil that our parents may have given us. There are plant sources of EFAs (i.e. flax) and animal sources (i.e. fish). Animal sources appear to be better absorbed and more effective than plant sources. There is a good and well thought out article on EFA's that can be found at PWS Playroom (http://www.pwsplayroom.com/efa.htm ).

These unsaturated fatty acids are easily used by your body to form the brain and the lipid layer around cells. Saturated fats (like butter) compete with unsaturated fats. There is some talk that ingestion of EFAs contributes to brain formation and intelligence. Have you heard about breast fed babies being smarter? If it is true, it is likely due to EFAs. Have you heard of fish being brain food? If this is true it is likely due to EFA's.

Check out the Cherab Foundation on EFAs (http://www.cherab.org/information/dietaryeffects/efabasics.html ). There is a lot of anecdotal evidence about fatty acids and language development. I found this story persuasive.

Finally, there is the role of these EFA's in metabolism. I haven't seen much discussion about this. I would welcome anyone's opinion as this is a stretch for me. But, there are a group of receptors called PPAR. They bind fatty acids and they are involved in numerous diseases including diabetes. Saturated fatty acids appear to bind them and initiate an inflammatory response that can have many bad downstream effects, such as heart disease. Unsaturated fatty acids compete for these receptors and have an anti-inflammatory effect. I am mulling this over...

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Sources

Nordic Naturals ProEFA. It can be found on http://www.speechville.com. You can order through the speechville site -- I know Kirkman labs and http://www.omega-direct.com handle this type. Other parents use the Natural Factors Rich Old Bend for Kid.

I have now switched to the Ultimate Omega formula. I am not convinced that we need more Omega-6's (present in the ProEFA blend) and would rather just supplement with the Omega-3's.

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Working them into your Diet

There is an interesting book called the Omega Diet that talks about oils. In my opinion, the book is a bit extreme, but makes really good points. I think that a diet high in flax oils and fish oils is good for most everyone.

I think that if you get into the groove it won't be so hard to incorporate. Maybe it will "work" and maybe it won't but probably you will all be healthier. There are many places to work in flax oil. There is a type of yummy bread made by Natural Ovens that has high levels of flax oils. They also make great (but expensive) snack bars. Plus, there are great frozen waffles with flax oil.

Fish can be eaten for fish oil and fish oil is pretty easy to take in capsule form. My whole family takes it. We call it "smart medicine."

The Omega Diet also mentions walnut oil and canola oil. I make my own salad dressings (oil and vinegar and spice) and switched from olive oil to walnut oil. It was pretty easy and tasty. I don't really bake, but keep thinking that bran muffins or banana nut bread made with walnut oil would probably be pretty tasty.

I am also a big honey person. When my kids want something sweet, I give them a teaspoonful of honey. They like it. Local honey is best if you can get it.

Also, this year we made the switch from regular potatoes to sweet potatoes. I am not sure what your guy would say about sweet potatoes, but they suit us well. It seems that you could do most anything with them that you could with real potatoes. Plus, they have the added benefit that you can add walnuts (and walnut oil??) and cinnamon and honey to them and call them dessert. :)

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Research

Nutr Health. 2004;18(1):3-27. Related Articles, Links

From superior adaptation and function to brain dysfunction--the neglect of epigenetic factors.

Saugstad LF.

Oslo Centre for Molecular Biology and Neuroscience, Institute for Basic Medical Sciences, University of Oslo, Norway.

With optimal pregnancy conditions (natural, enriched diet which includes fish) African (Digo) infants are 3-4 weeks ahead of European/American infants in sensorimotor terms at birth, and during the first year. Infants of semi-aquatic sea-gypsies swim before they walk, and have superior visual acuity compared with us. With adverse pregnancy behaviour (fear of fat, a trend to dieting), neglecting the need for brain fat to secure normal brain development and function, we run a risk of dysfunction--death. Sudden Infant Death Syndrome victims have depressed birth weight, lower levels of marine fat in brainstem than controls, and >80 suffer multiple hypoxic episodes prior to death. Depressed birth weight (more than 10% below mean) is seen in learning and behaviour disorders, and a trend towards weights of less than 3kg is increasing, which supports a rise in antenatal sub optimality. Given marine fat deficiency in pregnancy and infancy, neurons starved for fuel could delay myelination and maturation in the latest developed Frontal Lobes. The phylogenetic oldest Lateral Frontal Lobe System (feed-back mechanism etc.) derived from olfactory bulb-amygdala, which crosses in Anterior Commisure is probably spared, while the Medial Frontal Lobe System derived from Hippocampus-Cingulum and crosses in Corpus Callosum (delayed response task) is most likely affected. The rise in infantile autism (intact vision and hearing) with deficit in delayed response task only, could suggest a deficit in the Medial Frontal Lobe System. The human species is unique; 70% of total energy to the foetus goes to development of the brain, which mainly consists of marine fat. It undergoes pervasive regressive events, before birth, in infancy and at puberty. Minimal retraction of neuronal arborisation is advantageous. Attributable to adverse pregnancy childrearing practice, excessive retraction is likely prenatally and in infancy. Pubertal age affects the fundamental property of nervous tissue, excitability: excessive excitatory drive is seen in early, and a deficiency in late puberty. It is postulated that with adequate marine fat, there is probably no risk of psychopathology at the extremes, whereas a deficiency could lead to paroxysmal (subcortical) dysfunction in early puberty, and breakdown of cortical circuitry and cognitive dysfunctions in late puberty. The post-pubertal psychoses, schizophrenia and manic-depressive psychosis at the extremes of the pubertal age continuum, with contrasting excitability and biological treatment, are probably the result of continuous dietary deficiency, which has inactivated the expression of genes for myelin development and oligodendrocyte-related genes in their production of myelin. The beneficial effect of marine fat in both disorders, in other CNS disorders as well as in developmental dyslexia (DD) and ADHD among others, supports our usual diet is persistently deficient. We have neglected the similarity of our great brain to other mammals, and our marine heritage. Given the amount of marine fat needed to secure normal brain development and function is not known, nor the present dietary level, it seems unduly conjectural to postulate that a dietary deficiency in marine fat is causing brain dysfunction and death. However, all observations point in the same direction: our diet focusing on protein mainly, is deficient, the deficiency is most pronounced in maternal nutrition and in infancy.

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