Autism Therapy: evening primrose oil

definition of evening primrose oil: not yet defined.

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Clinical Biochemistry, by Meguid, NA, Atta HM, Gouda AS, and Khalil RO, published in 2008, summarized Nov 26, 2008

DHA fish oil and evening primrose oil may improve autistic behaviors in children.

This study was designed to first measure the levels of polyunsaturated fatty acids (PUFA) in children with autism and then give the children PUFA supplements to see if their behavior improved. The study was done in Egypt. The authors found that children with autism had decreased levels of three types of PUFAs when compared to controls: linolenic acid, docosahexaenoic acid (DHA), and arachidonic acid. These decreased levels were the same as those seen in earlier studies of children with autism. The authors found that PUFA supplements improved behavior, ability to concentrate, motor skills, and language in children with autism.


Pediatrics, by Richardson, AJ, and Montgomery P., published in 2005, summarized Nov 14, 2006

This article reports on the results of a well-controlled study showing that supplementation with essential fatty acids (EFAs) improves the reading, spelling, and behavior of children with dyspraxia (developmental coordination disorder or DCD).

Dyspraxia (DCD) is a disorder in which children have difficulty making normal movements. Children with DCD also have difficulty with learning, social interaction, and appropriate behavior. Children with autism are more likely than those in the general population to have DCD. It is already known that deficiencies in EFAs can produce problems in attention and behavior; this article tested whether supplementation with EFAs could improve the symptoms of children with DCD (ages 5-12). Children were randomly divided into two groups: 55 received EFA supplements, and 55 received placebo for three months. EFA supplements consisted of a daily dose of 80% fish oil and 20% evening primrose oil. This supplementation resulted in doses of 558 mg EPA and 174 mg DHA (both omega-3 fatty acids), as well as 60 mg alpha-linoleic acid (an omega-6 fatty acid), and 9.6 mg vitamin E (alpha-tocopherol). Each child's motor skills, reading, spelling, and behavior were rated by people who were blind to whether the child was receiving EFAs or placebo. There were no significant improvements in the motor skills of children receiving EFA treatment, but the reading, spelling, and behavior of these children did improve by the end of the three months as compared to children who had been receiving placebo. After the three-month period, children who had been receiving placebo began the same EFA supplementation treatment, and similar improvements were then seen in these children.


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