There is no good evidence to support the use of pharmacological treatments or supplements in people with Fragile X Syndrome in general or those with a diagnosis of Fragile X Syndrome and autism.
This article reviews the research on drug therapy for the treatment of symptoms of Fragile X Syndrome. Most of the studies that they reviewed were very small and therefore it was hard for the studies to see an effect from the drug if such an effect did exist. Most of the studies were also poorly designed. The authors noted that a poorly designed folic acid study showed promise that folic acid supplements (10 mg/day) may raise the IQ of young children with Fragile X syndrome. One small study showed found methylphenidate to be helpful for children with Fragile X syndrome, but the study was short and poorly designed.









Please comment on this autism topic.
Denial?
Oct 25, 2006 by AnonymousI wondered how I could miss the signs? I had two boys and they were all close in age. My oldest was three when Katie was born. Was I too busy to notice....maybe.
I don't remember talking to her much as a baby, she was just in tow while I cared for the others....maybe I didn't play enough games with her.....I quickly looked at past albums and some videos. She smiled and made eye contact....oh, there we were are all giggling together on the floor. There she is in her footsie pajamas at the gate watching me in the kitchen....
No, she wasn't ignored, as a matter of fact she was mommy's girl. She was such a good baby, would watch TV quietly or play with a set of crayons while I cleaned the house. She carried a blanket around and did this funny thing, she'd run it through her fingers and sometimes her toes. She's line up her crayons but would not color with them. She loved the teletubby figurines, but really just lined them up as well. And she loved to sit in boxes. Oh yea, and when we were outside, she'd lay on the ground and look up, I figured she was just taking it all in.
I can't even bear to ask friends if they ever noticed or had concerns. What could they have said...she was still a toddler.
OH, and the pediatrician. Wonderful man, but I hear this happens often..... I mention she's not talking or waving hi...he suggests to just give it time. Was he right? Sure he could have been, how many kids have burst of development making up for delays....lots....but a few more questions during our visit and he would have seen she may have had traits that might have suggested autism. Autism just began exploding up here at the time, I know it wasn't on his radar.
I had no time to beat myself up trying to figure out the why's. Truth is, we diagnosed her early enough. Was it shots, was it diet or genetics...who cares, just gotta fix it. Now, as a precaution, I don't get her combined MMR vaccines, we will do it separately. And flu shot...they have mercury free now....but you have to ask. Is it the Mercury, don't know, but know Mercury isn't good for you and I don't want to risk it.
Until Katie was nearly 3 she woke up nightly because of gas. During the same time we found out about the autism we did a lower GI, perhaps that would be it, and then we could fix it. The scope was clean, her intestines a beautiful and perfect pink (I couldn't believe he showed me the pictures). But, even still, we tried the Gluten-Casein free diet...which is very hard, but to no avail. She just grew out of it. But I know many kids that have similar issues and respond to the diet....I feel it's better to explore all options, just in case you hit the nail on the head!
It wasn't about chasing causes, but really trying to eliminate them. The only thing I didn't do was test for fragile X or do an MRI. She really didn't show anything that suggested either was appropriate. When I asked the doctor what we might do differently if she had fragile X, she said nothing. I knew a mother of children with fragile X....Autism was fine for me right now.