Autism Therapy: gastrointestinal (GI) tract

definition of gastrointestinal (GI) tract: Refers to the parts of the body involved in eating, drinking, digestion, all the way through to making waste products in the feces. These parts include the throat, stomach, intestines, and colon. The G.I. tract does not include kidneys and making urine.

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J Autism Dev Disord, by , published in 2009, summarized Nov 4, 2010

Children’s GI problems appear less likely to respond to autism treatment and therefore GI symptoms may need to be considered and treated when creating a treatment plan for a child with autism.

The purpose of this study was to study the GI problems in a large sample of children with autism. The authors studied 172 children who entered two large-scale autism drug therapy trials. The groups (GI problems and no GI problems) were the same with regards to sex, race, special education placement, and family background. It seemed that those children who had more GI problems also had more behavioral problems. Children with autism and GI problems also had more social problems than children without GI problems.


Research in Developmental Disabilities, by Sturmey, P., published in 2005, summarized Oct 13, 2009

Secretin therapy may result in short term improvement of language and social problems in children with autism.

Secretin is a hormone produced by the gastrointestinal tract that helps the body to digest food. Secretin has been proposed as a therapy to treat autism This review article includes 15 studies of secretin therapy for children with autism. All 15 studies were double-blind, randomized, and placebo-controlled. None of the studies showed that secretin therapy could help children with autism. Some of the studies showed that language and social skills did get better, but the improvements did not last long. Four studies said that secretin may help children with autism who also have gut problems, but the data in these studies were not strong.


Autism, by Smith, RA, published in 2009, summarized Oct 8, 2009

Children with autism may have more bowel trouble than mainstream school children, but about the same amount of bowel trouble as children with other developmental disorders.

This case control study compared 52 children with autism spectrum disorders to 35 children from special schools and 112 mainstream school children. There were more reports of constipation, diarrhea, and flatulence (farting) in children with autism spectrum disorders (ASD) as compared to mainstream school children. The children with autism had about the same bowel trouble reports as children attending special needs schools. Parent reports of digestive trouble ranged from 14-25% for the different conditions. Overall, 35% of parents of children with autism reported concern about their child's bowels.


J Spec Pediatr Nurs, by Bellando, J., and Lopez M., published in 2009, summarized Oct 7, 2009

The school nurse is the “front line” medical professional and may be an important part of the care of children with autism in school.

Children with autism may have a range of health issues and use a range of therapies during school. The school nurse may be most helpful if she knows about the treatments and medical conditions. Medical issues include seizures, gastrointestinal (GI) problems, sleep problems, and medications. The school nurse can also be a part of the individualized education plan (IEP) for the child with autism.


Denise Reynolds, a registered dietician, has provided some good suggestions for toilet training your child with autism. She reminds parents that there are milestones that must be reached before a child can be toilet trained, for example, knowing how to dress and undress, understanding the bodily clues needed to use the bathroom, and walking. She explains that sometimes kids with autism have gastrointestinal problems that need to be addressed before successful toilet training. She quotes from an referenced article by Danica Mamlet, Autism and Toilet Training, for motivation cues and potential social integration issues. “A system that uses picture icons with each step identified is recommended as a tool to teaching toilet independence. A consistent routine capitalizes on the autistic’s child need for repetition.” Other tips include a transition object such as a book or a toy and teaching your child words specific to the bathroom so he can communicate. Reynolds’ final reminder is that each child has his own timetable and some children take longer than others to toilet train.

Read original article: Potty Training Tips for An Autistic Child


The Medical Autism Clinic (MAC) affiliated with the University of Alabama, Birmingham, was created to be a "roadmap" for parents as they deal with the diagnosis of autism. MAC uses the talents and skills of specialists in "genetics, nutrition, occupational therapy, speech therapy, rehabilitation, sleep disorders and audiology in one location to expedite the evaluation of some of the medical problems seen in children with ASDs." While all these areas are supported, Myriam Peralta-Carcelen, M.D., the director of MAC says the focus is on "feeding, sensory, motor, sleep, gastrointestinal and nutritional problems." MAC attempts to address these issues in a thorough and interdependent way. Parents and their children are referred to MAC by their pediatricians; first they complete a questionnaire, and then the children are evaluated by Peralta-Carcelen and her staff. Having all services under one roof allows the parents to leave the appointment at MAC with a course of action and a list of resources.

Read original aritcle: New Medical Autism Clinic Gives Parents Roadmap for Care


The findings of a study involving hyperbaric oxygen therapy (HBOT), released at the U.S. Autism & Asperger Association, showed that children with autism underwent increased speech skills after therapy. HBOT has also been shown to help with sleep and gastrointestinal issues sometimes found in children with autism.

Read original article.


A Vanderbilt Kennedy Center for Research on Human Development study reports that a single gene mutation doubles a child's susceptibility to autism. There are multiple theories on why seemingly normal children seem to lose abilities they possessed and withdraw. This research suggests that the MET gene, with other vulnerable genes, and environment, may precipitate the onset of autism. Many parents have reported that their children suffered from gastrointestinal and immune disorders; it is not clear whether this is linked with autism. However, investigation into the MET gene may provide some light. The MET gene and MET receptor are important for brain growth, brain maturation, immune function and digestive repair. Read more .



Please comment on this autism topic.

Living Gluten Free – Right to Heal

Feb 22, 2010 by karmic health

By Sandi Star, CCN


After struggling for over 40 years with chronic migraines, IBS, Muscle and joint pain, fatigue, brain fog, asthma and a slew of other ailments and frustrations I decided to take a closer look at the cause rather than obsessing on the symptoms. I was tired of relying on doctors to give me answers and tired of the medications that only gave me side affects and little relief.


I had been committed to health and fitness for over 20 years, losing close to 50 pounds and 5 dress sizes, however I still had all the chronic conditions that played havoc in my life. I realized there was a key element missing and soon found out it was my reaction to gluten and dairy. I didn't know enough about food intolerance or allergies or at least put the two together. I never believed food could have such a serious impact on overall health let alone be the direct cause of my diseases. With what I know today I’m surprised my doctor didn’t put the connection together when he diagnosed me with Sjögren’s Syndrome (autoimmune disease). Sjögren’s is one of the symptoms of Celiac along with a long list as you will see below and nutrition plays a critical role in the healing process. By making the appropriate diet changes – (gluten and dairy free), I’ve managed to eliminate my migraines, IBS………etc., etc., and have the Sjögren’s Syndrome under control. Even better, I have eliminated all medications and use food and natural remedies for nutrition and overall health. Now that you know why I became a clinical nutritionist and why I started Karmic Health lets get into the details of why it’s so important to understand gluten and its relation to diseases.


Why the problem with gluten now? A lot has changed in the way we harvest food compared to 50 years ago. Some of the seed companies began engineering wheat kernels that could be more easily ground and produce fluffier flour to make the soft, delicious white bread for example had to have greater yields; it made more money for the farmer and increased sales.


Gluten is a composite of the proteins gliadin and glutenin. These exist, conjoined with starch, in the endosperms of some grass-related grains, notably wheat, rye, and barley.


Understanding what happens in the body and some of the symptoms will help millions of people who go undiagnosed. Celiac is the most common genetic disease of mankind (yet for every person diagnosed, 140 will go undiagnosed).


A wheat allergy is the body’s abnormal autoimmune response to a certain protein component of wheat; it’s exhibited by a severe sudden onset allergic reaction. Usual symptoms are immediate coughing, asthma, breathing difficulties, and/or projectile vomiting. It can cause life-threatening responses in allergic people. A true Wheat allergy affects less than 1/2 % of population. 


Intolerance's are much more common than true food allergies but are harder to diagnose. Food intolerance is an adverse reaction to food that does not involve the body's immune system. Generally food intolerance is an inability to properly digest certain foods. In some cases food passes right through the body before digestion is complete.


Leaky Gut is an increase in permeability of the intestinal mucosa to luminal macromolecules, antigens, and toxins associated with inflammatory degenerative and/ or atrophic mucosa or lining. Put more simply, large spaces develop between the cells of the gut wall allowing bacteria, toxins and food to leak into the bloodstream. Leaky Gut Syndrome has also been linked with many conditions, such as: Celiac Disease, Multiple Sclerosis, Fibromyalgia, Autism, Chronic Fatigue Syndrome, Irritable Bowel Syndrome, Eczema, Dermatitis, and Ulcerative Colitis. 


Celiac disease is an autoimmune disease caused by an inappropriate immune response to dietary proteins found in wheat, rye, and barley (gluten and


gliadin). This response leads to inflammation of the small intestine and to damage and destruction of the villi that line the intestinal wall. These villi are projections (small folds) that increase the surface area of the intestine and allow nutrients, vitamins, minerals, fluids, and electrolytes to be absorbed into the body. When the villi are destroyed, the body is much less capable of absorbing food and begins to develop symptoms associated with malnutrition and malabsorption. When the body is exposed to the gluten and gliadin proteins, it forms antibodies that recognize and act against not only the grain proteins, but also against constituents of the intestinal villi. As long as the patient continues to be exposed to the proteins, he will continue to produce these autoantibodies. Celiac disease is found throughout the world but is most prevalent in those of European descent. It can affect anyone at any age and is more common in women. It is thought to be an inherited tendency that is triggered by an environmental, emotional, or physical event – although the exact mechanism is not fully understood.


According to the National Digestive Diseases Information Clearinghouse, about 5 to 15% of close family members of a celiac disease patient will also have the condition.


Symptoms


There are literally dozens, if not hundreds, of symptoms of gluten intolerance. It all comes down to inflammation in the body! Many people believe the most common symptoms are gastrointestinal in nature - yet the majority of people with gluten intolerance (and celiac disease) have extraintestinal symptoms. 


The most common symptoms of celiac disease include:


Fatigue


• Addison’s disease (hormonal disorder)


Gastrointestinal distress (gas, bloating, diarrhea, constipation, vomiting, reflux)


• Headaches (including migraines)


• Infertility


• Mouth sores


• Weight loss/gain


• Inability to concentrate


• Moodiness/depression


• Amenorrhea/delayed menarche (menstrual cycles)


• Bone/joint/muscle pain


Dental enamel hypoplasia (dental enamel defect)


• Short stature


Seizures


• Tingling numbness in the legs 


The “cure” is a life long gluten free diet.


Making the Transition


1. Have a reality check. Remember this is a choice! If you want to feel lousy for the rest of your life and get worse as time goes on then continue eating gluten. If you want to start on a journey to heal; go gluten free


2. Give it time. It takes time to heal. Take the 45 day challenge.


Within this time frame you will notice the brain fog is gone. Your body will start adjusting to a healthy weight. Yes, you will lose the bloating and weight around the middle. Don’t be discouraged if it takes a little longer to feel 100%. 


3. Look at your current diet and go through your pantry and refrigerator to find the foods and meals you already eat that are gluten-free. You may need to keep a food journal if you haven't already.


Be sure to list condiments, ice creams, produce, snacks, and other foods.


This list will be helpful as you create menus around your new foods and give you encouragement that you're already on the right track!


4. Give yourself permission to eat things that you may have restricted from your diet before your diagnosis. Potato chips or GF cookies may not be appropriate for other people, but they are a treat in a GF diet in small doses of course. You will need to find treats for yourself initially as you adjust to this diet. Count calories after you are comfortable with your new way of eating, manage your portions instead.


Once you are comfortable with the switch start cutting back on refined grains, crackers, breads, etc., to help the gut heal quicker. In all honesty, bread will not be that important. It's all about taking baby steps! 


5. Look at your current menus and meals and find ways to eliminate gluten from your diet. Replace bread in sandwiches with GF bread or green leaf lettuce and add your favorite fixings and condiments. Have breakfast burritos with rice tortillas instead of toast and eggs. Look for GF hot and cold cereals (must not have barley malt) and have those handy for a snack or meal. Replace bread and crackers with tortilla or corn chips, brown rice cakes or popcorn. For example, chicken or tuna salad on rice cakes or scooped onto corn chips is delicious. Popcorn is a filling side dish with soup. Be on the lookout for meals on your current menus or the menus of friends and family that are naturally gluten-free (roasted chicken, baked sweet potatoes and steamed veggies, for example) and make them a staple on your new menus. Surf the internet, watch cooking shows and browse magazines for ideas and adapt them as you see fit.


6. Clear out any and all foods that have gluten, wheat, wheat flour, oats, oat flour, rye, semolina, or modified food starch from your pantry. This will allow you to see how close you are to living gluten-free already. If you have family members living with you who are not gluten free, you might consider giving the "offending edibles" to them to be put in another part of the house while you learn to live and think gluten-free. As time goes on you can cook for the entire family without gluten.


7. Plan and prepare your meals ahead of time. Being caught hungry without a plan is not a good idea! Keep a few GF soups on hand in case of extreme hunger. Keep a small cooler in your car with snacks such as nuts, dried fruit and water. It helps to outline and pack any meals you're eating at home and away from home, including snacks. An example could be -


o Breakfast: scrambled eggs and mixed vegetables rolled in a rice tortilla, sliced apples, and coffee.


o Lunch: Lettuce with turkey, avocado slices, tomato, and mustard, 1 oz. chips, and 2 organic dark chocolate pieces.


o Dinner: Grilled fish or chicken with mixed vegetables, wild rice, and fruit.


o Snacks: 1 oz. almonds and popcorn.


o Desert: Coconut Ice Cream or fruit. 


Tips


1. Be patient with yourself. You'll have days when being gluten-free is really depressing (maybe even "fall off the wagon"). This is normal.


Relax – it’s a process.


2. Carry snacks with you wherever you go. It's often difficult to find an appropriate snack when the hunger strikes. GF bars are great! 


3. Arrange with the hosts of gatherings you may attend to bring your own sides or complete meals. Most people are very supportive of restricted diets.


4. Carry a small cooler in your car with small cold packs to store fruit, snacks and water


5. Consider avoiding restaurants during your transition phase as you learn how to eat and think gluten-free. Grilled meats (over a flame), baked potatoes and salads without croutons are usually safe bets. But keep a log of places you eat, what you ate and how you felt afterward. Gluten is insidious and can turn up in the oddest places (french fries, for example which can be dusted with flour).


6. Get your hands on cookbooks or start collecting your own recipes in a binder. 


7. Carry digestive aids (enzyme and bioflavonoid) with you in case of accidental ingestion. There are ones specifically for gluten such as GlutenFlam by Apex Energetics; available from your healthcare practitioner.


8. Consider taking a multi-vitamin to make up for vitamins and minerals you may lack with your new diet (ask your doctor or nutritionist if necessary).


9. Find a mentor or support system.


10. Breathe


About the author: Sandi Star, CCN


Sandi is the founder of Karmic Health, specializing in nutrition related to disease where a gluten and casein (dairy) free lifestyle is crucial; working with celiac, autism and all auto immune disorders. Sandi graduated from The Natural Healing Institute with a degree in Clinical Nutrition and is continuing her studies in Clinical Herbology. She has hands on understanding of many health issues and has dedicated her life in helping others reach their optimal health.


For more information related to this article please visit www.karmic-health.com or contact Sandi Star at 760.685.3154


© Copyright Karmic Health 2010


Biomedical Treatments

Oct 25, 2006 by Anonymous

My daughter has improved enormously on a specific protocol of supplements, detoxification, and gf/cf, soy free, glutamate free, low sugar diet. It is not idiopathic as she regressed after 165 mcg of thimerosal. She is now being treated for toxic encephalopathy, gut dysbiosis, an inability to excrete heavy metals, immune dysfunction, and food intolerances.

I see nothing on this site about many autistic children having immune and gut dysfunction, nor any studies about inflammation at all.

Autism: A Novel Form of Mercury Poisoning.
Medical Hypothesis, 2001.
Sallie Bernard, Albert Enyati, Lynn Redwood, RN, Teresa Binstock, PhD.

Comparison of Blood and Brain Mercury Levels in Infant Monkeys Exposed to Methylmercury or Vaccines Containing Thimerosal.
Environmental Health Perspectives, Aug 2005.

Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors.
Neurotoxicology, Jan 2005.
S. Jill James, PhD [University of Arkansas].

Large Brains in Autism: The Challenge of Pervasive Abnormality.
The Neuroscientist, Volume 11, Number 5, 2005.
Martha Herbert, MD, PhD [Harvard University].

Neurotoxic Effects of Postnatal Thimerosal are Mouse Strain Dependent.
Molecular Psychiatry, Sep 2004.
Mady Hornig, MD [Columbia University].

Activation of Methionine Synthase by Insulin-like Growth Factor-1 and Dopamine: a Target for Neurodevelopmental Toxins and Thimerosal.
Molecular Psychiatry, July 2004.
Richard C. Deth, PhD [Northeastern University].

Neuroglial Activation and Neuroinflammation in the Brain of Patients with Autism.
Annals of Neurology, Feb 2005.
Diana L. Vargas, MD [Johns Hopkins University].

Reduced Levels of Mercury in First Baby Haircuts of Autistic Children
International Journal of Toxicology
Dr. Amy S. Holmes, Mark F. Blaxill, Boyd E. Haley, Ph.D.
March 14, 2003

Dysregulated Innate Immune Responses in Young Children with Autism Spectrum Disorders: Their Relationship to Gastrointestinal Symptoms and Dietary Intervention.
Neuropsychobiology, 2005.
Harumi Jyonouchi, MD [New Jersey Medical School].

http://www.autismwebsite.com/ari/index.htm

 

 



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  • Synonyms for gastrointestinal (GI) tract include: G.I., G.I. tract, gastrointestinal, GI, GI tract
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