Research summaries for autism therapy: Geodon (ziprasidone)

definition of Geodon (ziprasidone): Geodon® is an antipsychotic medication that may be prescribed for people with autism to help reduce hyperactivity, aggression, self-abusive behavior, temper tantrums, lability (mood swings), social withdrawal, and repetitive behaviors. Ziprasidone is currently in clinical trials to test effectiveness in children with autism. Some children have improved with treatment. Ziprasidone is indicated for schizophrenia, bipolar mania, and agitation in people with schizophrenia. Ziprasidone works as a dopamine and serotonin type 2 antagonist, and has other effects on the nervous system.
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The Role of Antipsychotics in the Management of Behavioral Symptoms in Children and Adolescents with Autism, Summarized Apr 27, 2009

Antipsychotic drugs may help to reduce problem behaviors and improve function in patients with autism.

Treatment of autism requires many approaches: educational, behavioral, and psychosocial. The purpose of this review article is to describe the use of antipsychotic drugs to treat symptoms of autism. The antipsychotics drugs include: haloperidol, risperidone, olanzapine, ziprasidone, aripiprazole, clozapine, and quetiapine. Haloperidol has been around for a long time and there are many studies that show haloperidol to be safe and effective. Risperidone is the antipsychotic drug that has been best studied in autism. Read more...

Atypical Antipsychotics in Children and Adolescents with Autistic and Other Pervasive Developmental Disorders, Summarized Sep 3, 2008

Drug therapy may help with problem behaviors that can be associated with autism.

This review article describes the use of a type of drug known as atypical antipsychotics as a treatment for children with autism, and reports on whether or not these drugs work. Atypical antipsychotics are often used as a first-line therapy to treat problem behaviors in children with autism. Problem behaviors such as aggression and self-injury and tantrums can often get in a way of a childâ??s schooling. Atypical antipsychotics include clozapine, risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole. Risperidone is the only drug that is FDA-approved for use with autism. Read more...

Ziprasidone in Adolescents with Autism: An Open-Label Pilot Study, Summarized Apr 17, 2008

Ziprasidone may help with the symptoms of autism.

This pilot study was designed to see if the antipsychotic ziprasidone is a safe and effective treatment for behavior problems that can come with autism. The study included only 12 teenagers. Ziprasidone does appear to reduce global and specific symptoms of autism. These symptoms were measured by the researchers and the parents. The researchers thought that the drug therapy worked better than the parents did. Read more...

Atypical Antipsychotics in Children with Pervasive Developmental Disorders, Summarized Oct 17, 2007

Several drugs can be used to help with symptoms of autism: risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole, or clozapine.

This review article describes the use of drug therapy (atypical antipsychotics) to treat autism. Drug therapy can be used to control symptoms of aggression, irritability, and hyperactivity. Of all the drugs used to treat autism, risperidone is the one that has been tested the most in research studies. Risperidone and other drugs like it can help symptoms of autism, but they can also cause weight gain. These types of drugs may also increase the risk for diabetes. Read more...

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Synonyms for Geodon (ziprasidone) include: Geodon, Geodon®, ziprasidone
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