Research summaries for autism therapy: immunoglobulin therapy

definition of immunoglobulin therapy: Therapy that uses immunoglobulins to treat the patient for a variety of health conditions including autism. The antibodies are usually given through an I.V. over the span of a couple of hours. The procedure is done in a medical setting, and the child can go home when it is done.
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A Double-Blind, Placebo-Controlled Trial of Oral Human Immunoglobulin for Gastrointestinal Dysfunction in Children with Autistic Disorder, Summarized Jul 14, 2009

People with autism may have digestive problems like diarrhea or constipation. One theory is that digestive trouble is due to inflammation (overactive immune system) in the gut. The authors tested whether oral immunoglobulin treatment might calm down the immune system in the gut and improve symptoms of autism.... Read more...

Oral Human Immunoglobulin for Children with Autism and Gastrointestinal Dysfunction: A Prospective, Open-Label Study, Summarized Mar 7, 2007

Treatment with oral immunoglobulin may improve gastrointestinal (GI) symptoms and behavior in children with autism.

About one quarter of children with autism have GI problems such as diarrhea or constipation. The twelve children in the study were fed nightly doses of 420 mg of immunoglobulin for eight weeks. Earlier studies have shown that about 50% of immunoglobulin that is eaten is biologically active in the gut. The study measured effect of immunoglobulin therapy on stool number, stool texture, and stomach tenderness. Oral immunoglobulin appeared to be safe treatment option for autism.
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