Autism Therapy: opioid

definition of opioid: not yet defined.

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Arch Dis Child, by Cass, H., Gringras P., March J., McKendrick I., OHare AE, Owen L., and Pollin C., published in 2008, summarized Oct 17, 2008

Urine tests for wheat- and milk-derived peptides are not likely to predict which children will respond to a gluten-free and/or casein-free diet.

Some people believe that children with autism suffer from a leaky gut which results in small proteins (peptides) being present in the urine. This study was designed to see whether peptides from wheat or milk were leaking from the gut and making their way into the urine of children with autism. The study did not find any of these small proteins (peptides) in the urine of the boys with autism or Asperger syndrome. The authors conclude that these urine tests are costly and not useful for choosing a diet therapy. The study did not look at whether or not gluten-free and/or casein-free diets are able to help children with autism.


Nutritional Neuroscience, by Evans, C., Dunstan RH, Rothkirch T., Roberts TK, Reichelt KL, Cosford R., Deed G., Ellis LB, and Sparkes DL, published in 2008, summarized Jul 15, 2008

Special diets may be able to help some children with autism.

Many children with autism have problems with their gut. Some people think that children with autism are not able to do a good job digesting some proteins and therefore they have little pieces of proteins that act on their brains (opioid peptides). This study looked at urine of children with autism to see how they break down and use protein and sugar. The study had 63 children with autism (aged 5-15 years) and used their 29 siblings as a control. The authors found that children with autism seem to break down protein and sugar differently than other children.


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