Research summaries for autism therapy: oral

definition of oral: Related to the mouth or speaking. For example, if someone needs to take a medication orally, they take it in their mouth.
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Treatment Outcomes for Severe Feeding Problems in Children with Autism Spectrum Disorder, Summarized Jun 1, 2010

Children with autism who have feeding problems may be helped by an interdisciplinary feeding program.

Feeding problems are a pattern of eating that is not normal and causes social or health problems for the patient. The purpose of this study was to see if a feeding program was able to help 46 children with autism who had feeding problems. The children (aged 3 to 12 years) in the study received intense behavior therapy and oral motor therapy. The authors found the program to be a success based upon one follow-up data point for each child. While the program was able to help the children, the authors note that these children had severe feeding issues and were part of a feeding disorders program.

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Safety and Efficacy of Oral DMSA Therapy for Children with Autism Spectrum Disorders: Part B – Behavioral Results, Summarized Apr 27, 2010

A single round of DMSA chelation therapy may improve the severity of autism.

The purpose of this study was to see if DMSA therapy is safe and helpful for children with autism. The authors used five tools to assess changes in autism symptoms. Three of the tools (PDD-BI, SAS and PGI) showed improved behaviors in the children who were given one round of DMSA therapy, and those who were given seven rounds of DMSA therapy. The authors believe that one round of treatment may be enough for some children to excrete toxic metals. The children who released the most metals (thallium, arsenic, mercury, and lead) were the ones with the most improved autism symptoms.

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Safety and Efficacy of Oral DMSA Therapy for Children with Autism Spectrum Disorders: Part A – Medical Results, Summarized Mar 4, 2010

Oral dimercapto succinic acid (DMSA) therapy may be helpful in normalizing red blood cell glutathione levels in children with autism.

This study was designed to see if DMSA therapy (9 doses over 3 days, 10 mg/kg-dose) would cause children with autism to excrete toxic metals. DMSA was very good at causing lead to be released from the body. The children seemed to have less lead in their bodies after treatment than children in other research studies. Children were given 3 rounds of DMSA treatment. Researchers said that 80% of the children may need more than three rounds of DMSA treatment in order to remove all of the toxic metals. The authors said that DMSA therapy may reduce toxic metals and improve glutathione levels with few apparent side effects.

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A Double-Blind, Placebo-Controlled Trial of Oral Human Immunoglobulin for Gastrointestinal Dysfunction in Children with Autistic Disorder, Summarized Jul 14, 2009

Oral immune therapy does not seem to improve digestive problems in children with autism. People with autism may have digestive problems like diarrhea or constipation. One theory is that digestive trouble is due to inflammation (overactive immune system) in the gut. The authors tested whether oral immunoglobulin treatment might calm down the immune system in the gut and improve symptoms of autism.... Read more...

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