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Healing Thresholds Autism Therapy Topic Feed http://autism.healingthresholds.com/therapy/paxil-paroxetine/feed en High-Dose Paroxetine Treatment for an Adolescent with Obsessive-Compulsive Disorder Comorbid with Asperger’s Disorder http://autism.healingthresholds.com/research/high-dose-paroxetine-treatment-adolescent-obsessive-compulsive-disorder-comorbid-asperger-s <div id="biblio-node"><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.atitle=High-Dose+Paroxetine+Treatment+for+an+Adolescent+with+Obsessive-Compulsive+Disorder+Comorbid+with+Asperger%E2%80%99s+Disorder&rft.title=Psychiatry+and+Clinical+Neurosciences&rft.date=2009&rft.volume=63&rft.issue=2&rft.spage=251&rft.epage=256&rft.aulast=Sasayama&rft.auinit=D"></span><table> <tbody> <tr class="odd"><td class="biblio-row-title biblio-field-title-title">Title</td><td class="biblio-field-contents-title">High-Dose Paroxetine Treatment for an Adolescent with Obsessive-Compulsive Disorder Comorbid with Asperger’s Disorder</td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-type">Publication Type</td><td class="biblio-field-contents-type">Journal Article</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-authors">Authors</td><td class="biblio-field-contents-authors"><a href="/research-index/author/1978">Sasayama D</a>, <a href="/research-index/author/1979">Sugiyama N</a>, <a href="/research-index/author/1980">Imai J</a>, <a href="/research-index/author/1981">Hayashida A</a>, <a href="/research-index/author/1982">Harada Y</a>, <a href="/research-index/author/1983">Amano N</a></td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-secondary-title">Journal Title</td><td class="biblio-field-contents-secondary-title">Psychiatry and Clinical Neurosciences</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-year">Year of Publication</td><td class="biblio-field-contents-year">2009</td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-volume">Volume</td><td class="biblio-field-contents-volume">63</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-issue">Issue</td><td class="biblio-field-contents-issue">2</td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-pages">Pages</td><td class="biblio-field-contents-pages">251-256</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-url">URL for Abstract</td><td class="biblio-field-contents-url"><a href="http://www.ncbi.nlm.nih.gov/pubmed/19335398?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum">http://www.ncbi.nlm.nih.gov/pubmed/19335398?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum</a></td> </tr> <tr class="even"><td valign="top">Full Text</td><td> <p><a class="glossary-term" href="/therapy/paxil-paroxetine"><cite title=" Paroxetine is an antidepressant that is a type of selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a neurotransmitter in the brain, which helps to improve certain mood problems. Paxil® is prescribed for depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder, and premenstrual dysphoric disorder. It may also be prescribed for people with autism. One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.">Paroxetine</cite></a> may help to treat fears and <a class="glossary-term" href="/therapy/anxiety"><cite title=" Distress or uneasiness caused by fear of something bad that might happen. People with autism can have anxiety about things that most people do not feel anxious about. ">anxiety</cite></a> in people with <a class="glossary-term" href="/therapy/autism"><cite title=" Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).">autism</cite></a>.</p> <p>Many people with <a class="glossary-term" href="/therapy/autism"><cite title=" Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).">autism</cite></a> also have <a class="glossary-term" href="/therapy/obsessive-compulsive-disorder-ocd"><cite title=" Type of anxiety disorder with obsessive thoughts and/or repetitive behaviors. Obsessive thoughts are thoughts not based in reality that focus on something so much that it affects normal daily life. Examples of repetitive behaviors or rituals include cleaning, washing hands, or counting. Rituals are often performed with hopes of making obsessive thoughts go away. When people with OCD do these rituals and other people notice, it often increases their anxiety even more.">obsessive compulsive disorder</cite></a> (<a class="glossary-term" href="/therapy/obsessive-compulsive-disorder-ocd"><cite title=" Type of anxiety disorder with obsessive thoughts and/or repetitive behaviors. Obsessive thoughts are thoughts not based in reality that focus on something so much that it affects normal daily life. Examples of repetitive behaviors or rituals include cleaning, washing hands, or counting. Rituals are often performed with hopes of making obsessive thoughts go away. When people with OCD do these rituals and other people notice, it often increases their anxiety even more.">OCD</cite></a>). This <a class="glossary-term" href="/therapy/case-study"><cite title=" Intensive study of a single child with the intention of generalizing the findings to a larger population. ">case study</cite></a> describes a 15-year-old girl with <a class="glossary-term" href="/therapy/asperger-syndrome"><cite title=" Neurobiological pervasive developmental disorder that is characterized by deficiencies in social and communication skills. Individuals with Asperger (or Asperger's) syndrome often have average or above average intelligence and typical language development. Asperger syndrome can be difficult to diagnose.">Asperger syndrome</cite></a> and <a class="glossary-term" href="/therapy/obsessive-compulsive-disorder-ocd"><cite title=" Type of anxiety disorder with obsessive thoughts and/or repetitive behaviors. Obsessive thoughts are thoughts not based in reality that focus on something so much that it affects normal daily life. Examples of repetitive behaviors or rituals include cleaning, washing hands, or counting. Rituals are often performed with hopes of making obsessive thoughts go away. When people with OCD do these rituals and other people notice, it often increases their anxiety even more.">OCD</cite></a> who was prescribed high-dose <a class="glossary-term" href="/therapy/paxil-paroxetine"><cite title=" Paroxetine is an antidepressant that is a type of selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a neurotransmitter in the brain, which helps to improve certain mood problems. Paxil® is prescribed for depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder, and premenstrual dysphoric disorder. It may also be prescribed for people with autism. One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.">paroxetine</cite></a> <a class="glossary-term" href="/therapy/treatment"><cite title=" Something given to or performed on a person to improve health or behaviors. A treatment can include medical interventions such as giving medications. A treatment can also include non-medical interventions such as acupuncture. A treatment is usually considered something done in limited numbers. A series of treatments is often called therapy.">treatment</cite></a>. The girl became obsessive when she was in grade <a class="glossary-term" href="/therapy/school"><cite title=" Type of school that is supported through government funds.">school</cite></a> and would work for hours to write her homework neatly. She was placed in the hospital because of her severe fear of germs and prescribed <a class="glossary-term" href="/therapy/paxil-paroxetine"><cite title=" Paroxetine is an antidepressant that is a type of selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a neurotransmitter in the brain, which helps to improve certain mood problems. Paxil® is prescribed for depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder, and premenstrual dysphoric disorder. It may also be prescribed for people with autism. One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.">paroxetine</cite></a> at 60 mg/day and given behavior <a class="glossary-term" href="/therapy/therapy"><cite title=" Intervention intended to help people with autism improve their health and behaviors. Therapy usually implies repeated sessions of treatments or activities. For example, speech therapy involves repeated visits with a trained therapist (or specialist) who works with the child to improve speech.">therapy</cite></a>. Her fears went away with the <a class="glossary-term" href="/therapy/treatment"><cite title=" Something given to or performed on a person to improve health or behaviors. A treatment can include medical interventions such as giving medications. A treatment can also include non-medical interventions such as acupuncture. A treatment is usually considered something done in limited numbers. A series of treatments is often called therapy.">treatment</cite></a>, but the <a class="glossary-term" href="/therapy/obsessive-compulsive-disorder-ocd"><cite title=" Type of anxiety disorder with obsessive thoughts and/or repetitive behaviors. Obsessive thoughts are thoughts not based in reality that focus on something so much that it affects normal daily life. Examples of repetitive behaviors or rituals include cleaning, washing hands, or counting. Rituals are often performed with hopes of making obsessive thoughts go away. When people with OCD do these rituals and other people notice, it often increases their anxiety even more.">OCD</cite></a> remained.</p> </td> </tr> </tbody> </table> </div> anxiety Asperger Syndrome autism case study comorbidity drug obsessive-compulsive disorder (OCD) Paxil (paroxetine) school therapy treatment Tue, 12 May 2009 17:38:36 +0000 scottie 3257 at http://autism.healingthresholds.com Retrial of Selective Serotonin Reuptake Inhibitors in Children with Pervasive Developmental Disorders: A Retrospective Chart Review http://autism.healingthresholds.com/research/retrial-selective-serotonin-reuptake-inhibitors-children-pervasive-developmental-disorders- <div id="biblio-node"><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.atitle=Retrial+of+Selective+Serotonin+Reuptake+Inhibitors+in+Children+with+Pervasive+Developmental+Disorders%3A+A+Retrospective+Chart+Review&rft.title=Journal+of+Child+and+Adolescent+Psychopharmacology&rft.date=2009&rft.volume=19&rft.issue=2&rft.spage=111&rft.epage=117&rft.aulast=Henry&rft.aufirst=CA"></span><table> <tbody> <tr class="odd"><td class="biblio-row-title biblio-field-title-title">Title</td><td class="biblio-field-contents-title">Retrial of Selective Serotonin Reuptake Inhibitors in Children with Pervasive Developmental Disorders: A Retrospective Chart Review</td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-type">Publication Type</td><td class="biblio-field-contents-type">Journal Article</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-authors">Authors</td><td class="biblio-field-contents-authors"><a href="/research-index/author/1962">Henry CA</a>, <a href="/research-index/author/1963">Shervin D</a>, <a href="/research-index/author/1964">Neumeyer A</a>, <a href="/research-index/author/1965">Steingard R</a>, <a href="/research-index/author/1966">Spybrook J</a>, <a href="/research-index/author/1967">Choueiri R</a>, <a href="/research-index/author/1968">Bauman M</a></td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-secondary-title">Journal Title</td><td class="biblio-field-contents-secondary-title">Journal of Child and Adolescent Psychopharmacology</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-year">Year of Publication</td><td class="biblio-field-contents-year">2009</td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-volume">Volume</td><td class="biblio-field-contents-volume">19</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-issue">Issue</td><td class="biblio-field-contents-issue">2</td> </tr> <tr class="even"><td class="biblio-row-title biblio-field-title-pages">Pages</td><td class="biblio-field-contents-pages">111-117</td> </tr> <tr class="odd"><td class="biblio-row-title biblio-field-title-url">URL for Abstract</td><td class="biblio-field-contents-url"><a href="http://www.ncbi.nlm.nih.gov/pubmed/19364289?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum">http://www.ncbi.nlm.nih.gov/pubmed/19364289?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum</a></td> </tr> <tr class="even"><td valign="top">Full Text</td><td> <p>SSRI <a class="glossary-term" href="/therapy/drug"><cite title=" Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. ">drug therapy</cite></a> may not be helpful for children with <a class="glossary-term" href="/therapy/autism"><cite title=" Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).">autism</cite></a>.</p> <p>Many youths with <a class="glossary-term" href="/therapy/autism"><cite title=" Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).">autism</cite></a> do not respond well to SSRI (selective <a class="glossary-term" href="/therapy/serotonin"><cite title=" Chemical that is a neurotransmitter in the central nervous system. Serotonin is produced by certain types of neurons and by certain cells in the gastrointestinal tract. Serotonin is important in regulating mood, sleep, body temperature, appetite, and other processes in the body. ">serotonin</cite></a> reuptake inhibitors) <a class="glossary-term" href="/therapy/drug"><cite title=" Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. ">drug therapy</cite></a> (<a class="glossary-term" href="/therapy/paxil-paroxetine"><cite title=" Paroxetine is an antidepressant that is a type of selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a neurotransmitter in the brain, which helps to improve certain mood problems. Paxil® is prescribed for depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder, and premenstrual dysphoric disorder. It may also be prescribed for people with autism. One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.">paroxetine</cite></a>, <a class="glossary-term" href="/therapy/prozac-sarafem-fluoxetine-hydrochloride"><cite title=" Prozac® and Sarafem® are antidepressants that may be prescribed for people with autism to help decrease aggression and depression. It can also help reduce repetitive behaviors, and improve language and social interactions. In some individuals, fluoxetine can make these symptoms worse, so each individual must be monitored closely. Fluoxetine is indicated for depression, obsessive-compulsive disorder, bulimia nervosa, and panic disorder in children and adults. This medication is a serotonin reuptake inhibitor (SSRI). One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.">fluoxetine</cite></a>, <a class="glossary-term" href="/therapy/zoloft-sertraline-hydrochloride"><cite title=" Zoloft® is an antidepressant that may be prescribed to help reduce anxiety and repetitive behaviors in people with autism. Zoloft® is indicated for major depressive disorder, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder. This medication is a serotonin reuptake inhibitor (SSRI). One possible serious side effect is increased risk of suicidal thinking and behavior in children, adolescents, and young adults. The risk of this side effect needs to be weighed carefully with the clinical need. Families should be aware of the need for close observation of the child or adolescent taking this medication, and maintain communication with the doctor who prescribed it.">sertraline</cite></a>, etc.). This study reports on the outcome of youths with <a class="glossary-term" href="/therapy/autism"><cite title=" Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).">autism</cite></a> who received a second round of SSRI <a class="glossary-term" href="/therapy/therapy"><cite title=" Intervention intended to help people with autism improve their health and behaviors. Therapy usually implies repeated sessions of treatments or activities. For example, speech therapy involves repeated visits with a trained therapist (or specialist) who works with the child to improve speech.">therapy</cite></a> after <a class="glossary-term" href="/therapy/treatment"><cite title=" Something given to or performed on a person to improve health or behaviors. A treatment can include medical interventions such as giving medications. A treatment can also include non-medical interventions such as acupuncture. A treatment is usually considered something done in limited numbers. A series of treatments is often called therapy.">treatment</cite></a> failure on a first SSRI. Only one third of children who received a second round of SSRI <a class="glossary-term" href="/therapy/therapy"><cite title=" Intervention intended to help people with autism improve their health and behaviors. Therapy usually implies repeated sessions of treatments or activities. For example, speech therapy involves repeated visits with a trained therapist (or specialist) who works with the child to improve speech.">therapy</cite></a> had a good response to the second SSRI <a class="glossary-term" href="/therapy/therapy"><cite title=" Intervention intended to help people with autism improve their health and behaviors. Therapy usually implies repeated sessions of treatments or activities. For example, speech therapy involves repeated visits with a trained therapist (or specialist) who works with the child to improve speech.">therapy</cite></a>. This response rate was low and was lower than has been shown in other studies. The authors also found that side effects were common on the SSRI <a class="glossary-term" href="/therapy/therapy"><cite title=" Intervention intended to help people with autism improve their health and behaviors. Therapy usually implies repeated sessions of treatments or activities. For example, speech therapy involves repeated visits with a trained therapist (or specialist) who works with the child to improve speech.">therapy</cite></a>.</p> </td> </tr> </tbody> </table> </div> anxiety autism Celexa (citalopram) drug Paxil (paroxetine) pervasive developmental disorder (PDD) Prozac - Sarafem (fluoxetine hydrochloride) serotonin therapy treatment Zoloft (sertraline hydrochloride) Wed, 06 May 2009 19:28:44 +0000 scottie 3249 at http://autism.healingthresholds.com