Aripiprazole (Abilify®) may be helpful for children and adolescents with autism who have severe behavioral problems.
This article describes a study of 34 autism patients (4-15 years old) who had severe behavioral problems such as aggression, self injury, and hyperactivity. These patients were treated through a psychiatric hospital (inpatient or outpatient) because of their severe behavioral problems. Patients were treated with 3-13 mg/day of aripiprazole for at least 12 weeks. The authors tested skills and behaviors between 4-12 months after the start of treatment. Of all the patients in the study, 37% were much improved or very much improved, and 29% had no change or got worse. Side effects were agitation (27% of patients) and sleep problems (15% of patients).









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