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Adding cholesterol to the diet may help certain forms of autism.
In most cases, it is not known what causes autism in a specific child. Some people with autism, however, have Smith-Lemli-Opitz syndrome (SLOS). SLOS happens because one of the genes in the body is broken (inborn error of metabolism). As a result, people with SLOS do not use cholesterol well and need extra cholesterol. Most people with SLOS also have wide-set eyes, low-set ears, and a high arched palate in the mouth.
Energy supplements such as creatine, biotin, and ribose may help some children with autism.
This review article describes different energy problems that can cause the symptoms of autism. These are called inborn errors of metabolism and can include: phenylketonuria, creatine deficiency syndromes, and Smith-Lemli-Opitz Syndrome. The authors believe that these inborn errors of metabolism may account for 5% of the cases of autism. In several of the case studies that were reviewed, a person with autism was found to have a metabolic problem. The authors suggest that people with autism be tested for metabolic problems so that treatments can be tailored to any problems that might exist.
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