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    <title>Healing Thresholds Autism Therapy Topic Feed</title>
    <link>http://autism.healingthresholds.com/therapy/stablon-coaxil-tatinol-tianeptine/feed</link>
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    <title>Psychopharmacology of Aggression in Children and Adolescents with Autism: A Critical Review of Efficacy and Tolerability</title>
    <link>http://autism.healingthresholds.com/research/psychopharmacology-aggression-children-and-adolescents-autism-critical-review-efficacy-and-</link>
    <description>&lt;div id=&quot;biblio-node&quot;&gt;&lt;span class=&quot;Z3988&quot; title=&quot;ctx_ver=Z39.88-2004&amp;amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;amp;rft.atitle=Psychopharmacology+of+Aggression+in+Children+and+Adolescents+with+Autism%3A+A+Critical+Review+of+Efficacy+and+Tolerability&amp;amp;rft.title=Journal+of+Child+and+Adolescent+Psychopharmacology&amp;amp;rft.date=2008&amp;amp;rft.volume=18&amp;amp;rft.issue=2&amp;amp;rft.spage=157&amp;amp;rft.epage=178&amp;amp;rft.aulast=Parikh&amp;amp;rft.aufirst=MS&quot;&gt;&lt;/span&gt;&lt;table&gt;
&lt;tbody&gt;
 &lt;tr class=&quot;odd&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-title&quot;&gt;Title&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-title&quot;&gt;Psychopharmacology of Aggression in Children and Adolescents with Autism: A Critical Review of Efficacy and Tolerability&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;even&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-type&quot;&gt;Publication Type&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-type&quot;&gt;Journal Article&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;odd&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-authors&quot;&gt;Authors&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-authors&quot;&gt;&lt;a href=&quot;/research-index/author/1415&quot;&gt;Parikh MS&lt;/a&gt;, &lt;a href=&quot;/research-index/author/1416&quot;&gt;Kolevzon A&lt;/a&gt;, &lt;a href=&quot;/research-index/author/219&quot;&gt;Hollander E&lt;/a&gt;&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;even&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-secondary-title&quot;&gt;Journal Title&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-secondary-title&quot;&gt;Journal of Child and Adolescent Psychopharmacology&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;odd&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-year&quot;&gt;Year of Publication&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-year&quot;&gt;2008&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;even&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-volume&quot;&gt;Volume&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-volume&quot;&gt;18&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;odd&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-issue&quot;&gt;Issue&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-issue&quot;&gt;2&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;even&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-pages&quot;&gt;Pages&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-pages&quot;&gt;157-178&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;odd&quot;&gt;&lt;td class=&quot;biblio-row-title biblio-field-title-url&quot;&gt;URL for Abstract&lt;/td&gt;&lt;td class=&quot;biblio-field-contents-url&quot;&gt;&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/18439113?ordinalpos=1&amp;amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&quot;&gt;http://www.ncbi.nlm.nih.gov/pubmed/18439113?ordinalpos=1&amp;amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&lt;/a&gt;&lt;/td&gt; &lt;/tr&gt;
 &lt;tr class=&quot;even&quot;&gt;&lt;td valign=&quot;top&quot;&gt;Full Text&lt;/td&gt;&lt;td&gt; &lt;p&gt;Five &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/drug&quot;&gt;&lt;cite title=&quot; Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. &quot;&gt;drugs&lt;/cite&gt;&lt;/a&gt; have been shown to help with &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/aggressive-behavior&quot;&gt;&lt;cite title=&quot; Behavior or action that intrudes on others and may be harmful to others. Aggressive behaviors may be physical or verbal.&quot;&gt;aggression&lt;/cite&gt;&lt;/a&gt; in children with &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/autism&quot;&gt;&lt;cite title=&quot; Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).&quot;&gt;autism&lt;/cite&gt;&lt;/a&gt;: &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/stablon-coaxil-tatinol-tianeptine&quot;&gt;&lt;cite title=&quot; Other trade names are Coaxil® (Europe) and Tatinol® (Asia and Latin America). Drug currently approved for use in France that is an antidepressant. Tianeptine is a serotonin reuptake enhancer. This mechanism of action differs from many antidepressants that are serotonin reuptake inhibitors. Tianeptine has also been used to treat asthma in children, erectile dysfunction in men, and Attention Deficit Hyperactivity Disorder (ADHD). &quot;&gt;tianeptine&lt;/cite&gt;&lt;/a&gt;, &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/ritalin-methylin-methylphenidate-hydrochloride&quot;&gt;&lt;cite title=&quot; Ritalin®, Ritalin LA®, Methylin Oral®, or Methylin® are mild central nervous system stimulants that may be prescribed for people with autism to help reduce hyperactivity and repetitive movements. Methylphenidate is indicated for treatment of attention deficit disorder (ADD), attention-deficit/hyperactivity disorder (ADHD), and narcolepsy (falling asleep at the wrong times).&quot;&gt;methylphenidate&lt;/cite&gt;&lt;/a&gt;, &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/risperdal-risperidone&quot;&gt;&lt;cite title=&quot; 1) aggression, irritability, and severe behavior problems in autistic children 5-16 years old; 2) bipolar mania in individuals 10 years old and up; and 3) schizophrenia in adolescents and adults. Side effects might include weight gain, increased appetite, and sleepy or groggy feelings. Risperdal Consta, an injectable form of risperidone, is usually used to treat schizophrenia in adults. &quot;&gt;risperidone&lt;/cite&gt;&lt;/a&gt;, &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/catapres-duraclon-clonidine&quot;&gt;&lt;cite title=&quot; Catapres® (generic name clonidine) is usually prescribed to treat high blood pressure by relaxing blood vessels and reducing cardiac output. It has also been used to help alcohol withdrawal, tobacco smoking withdrawal, and diabetic diarrhea. It has been prescribed off-label in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and Tourette’s Syndrome. Catapres is available as tablets and transdermal patches.  Duraclon® is in the form of epidural injections, which are made directly into the nervous system through the spine.  It is primarily limited to relief of severe pain, as in cancer patients.&quot;&gt;clonidine&lt;/cite&gt;&lt;/a&gt;, and &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/revia-vivitrol-naltrexone&quot;&gt;&lt;cite title=&quot; This medication may be prescribed for autistic children to help improve ability to socialize and make eye contact, and also to help reduce pain sensitivity, self-injury behaviors, and repetitive behaviors. Revia® is indicated for people who are trying to stop an addiction to alcohol or opioids (e.g., morphine or heroin). This drug is an opioid antagonist, so it binds to opioid receptors and blocks the binding of alcohol or other drugs to the receptors, thus blocking the opiates from having an effect so the person will stop their addiction. Some children with autism have higher than normal levels of beta-endorphins in their nervous system, and naltrexone can lower beta-endorphin levels. An extended release injectable form is also available and is called Vivitrol®. &quot;&gt;naltrexone&lt;/cite&gt;&lt;/a&gt;.&lt;/p&gt;
&lt;p&gt;This review article describes studies on the use of &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/drug&quot;&gt;&lt;cite title=&quot; Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. &quot;&gt;drug therapy&lt;/cite&gt;&lt;/a&gt; used to treat &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/aggressive-behavior&quot;&gt;&lt;cite title=&quot; Behavior or action that intrudes on others and may be harmful to others. Aggressive behaviors may be physical or verbal.&quot;&gt;aggression&lt;/cite&gt;&lt;/a&gt; in children with &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/autism&quot;&gt;&lt;cite title=&quot; Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).&quot;&gt;autism&lt;/cite&gt;&lt;/a&gt;. The best research supports the use of &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/risperdal-risperidone&quot;&gt;&lt;cite title=&quot; 1) aggression, irritability, and severe behavior problems in autistic children 5-16 years old; 2) bipolar mania in individuals 10 years old and up; and 3) schizophrenia in adolescents and adults. Side effects might include weight gain, increased appetite, and sleepy or groggy feelings. Risperdal Consta, an injectable form of risperidone, is usually used to treat schizophrenia in adults. &quot;&gt;risperidone&lt;/cite&gt;&lt;/a&gt; and &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/ritalin-methylin-methylphenidate-hydrochloride&quot;&gt;&lt;cite title=&quot; Ritalin®, Ritalin LA®, Methylin Oral®, or Methylin® are mild central nervous system stimulants that may be prescribed for people with autism to help reduce hyperactivity and repetitive movements. Methylphenidate is indicated for treatment of attention deficit disorder (ADD), attention-deficit/hyperactivity disorder (ADHD), and narcolepsy (falling asleep at the wrong times).&quot;&gt;methylphenidate&lt;/cite&gt;&lt;/a&gt; to treat symptoms of &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/aggressive-behavior&quot;&gt;&lt;cite title=&quot; Behavior or action that intrudes on others and may be harmful to others. Aggressive behaviors may be physical or verbal.&quot;&gt;aggression&lt;/cite&gt;&lt;/a&gt; in children with &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/autism&quot;&gt;&lt;cite title=&quot; Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).&quot;&gt;autism&lt;/cite&gt;&lt;/a&gt;. The authors believe that future research should look to see if a class of &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/drug&quot;&gt;&lt;cite title=&quot; Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. &quot;&gt;drugs&lt;/cite&gt;&lt;/a&gt; known as &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/serotonin&quot;&gt;&lt;cite title=&quot; Chemical that is a neurotransmitter in the central nervous system. Serotonin is produced by certain types of neurons and by certain cells in the gastrointestinal tract. Serotonin is important in regulating mood, sleep, body temperature, appetite, and other processes in the body. &quot;&gt;serotonin&lt;/cite&gt;&lt;/a&gt; reuptake inhibitors can also help treat &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/aggressive-behavior&quot;&gt;&lt;cite title=&quot; Behavior or action that intrudes on others and may be harmful to others. Aggressive behaviors may be physical or verbal.&quot;&gt;aggression&lt;/cite&gt;&lt;/a&gt;. In all cases the authors suggest that studies start with a low dosage of &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/drug&quot;&gt;&lt;cite title=&quot; Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. &quot;&gt;drug&lt;/cite&gt;&lt;/a&gt; and slowly increase the amount of &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/drug&quot;&gt;&lt;cite title=&quot; Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. &quot;&gt;drug&lt;/cite&gt;&lt;/a&gt;. The authors also suggest that all future studies of &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/autism&quot;&gt;&lt;cite title=&quot; Neurodevelopmental brain disorder that is characterized by deficits in social interactions and ability to communicate (verbal and nonverbal). People with autism often have atypical patterns of interest or behavior. The term “autism” is commonly used as a general term to include several disorders that fall under the category of autism spectrum disorders (ASD) which are sometimes also called pervasive developmental disorders (PDD).&quot;&gt;autism&lt;/cite&gt;&lt;/a&gt; look to see if the &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/drug&quot;&gt;&lt;cite title=&quot; Chemical or medication that leads to changes in the body, usually with the goal of improving health. In some cases drugs can be abused, as in illegal drugs. Drugs include medications prescribed by medical professionals, as well as over-the-counter (OTC) medications. &quot;&gt;drug&lt;/cite&gt;&lt;/a&gt; is able to help with &lt;a class=&quot;glossary-term&quot; href=&quot;/therapy/aggressive-behavior&quot;&gt;&lt;cite title=&quot; Behavior or action that intrudes on others and may be harmful to others. Aggressive behaviors may be physical or verbal.&quot;&gt;aggression&lt;/cite&gt;&lt;/a&gt;.&lt;/p&gt;
 &lt;/td&gt; &lt;/tr&gt;
&lt;/tbody&gt;
&lt;/table&gt;
&lt;/div&gt;</description>
     <category domain="http://autism.healingthresholds.com/therapy/aggressive-behavior">aggressive behavior</category>
 <category domain="http://autism.healingthresholds.com/therapy/autism">autism</category>
 <category domain="http://autism.healingthresholds.com/therapy/catapres-duraclon-clonidine">Catapres - Duraclon (clonidine)</category>
 <category domain="http://autism.healingthresholds.com/therapy/concerta-methylphenidate-hydrochloride">Concerta (methylphenidate hydrochloride)</category>
 <category domain="http://autism.healingthresholds.com/therapy/drug">drug</category>
 <category domain="http://autism.healingthresholds.com/therapy/revia-vivitrol-naltrexone">Revia - Vivitrol (naltrexone)</category>
 <category domain="http://autism.healingthresholds.com/therapy/risperdal-risperidone">Risperdal (risperidone)</category>
 <category domain="http://autism.healingthresholds.com/therapy/ritalin-methylin-methylphenidate-hydrochloride">Ritalin - Methylin (methylphenidate hydrochloride)</category>
 <category domain="http://autism.healingthresholds.com/therapy/serotonin">serotonin</category>
 <category domain="http://autism.healingthresholds.com/therapy/stablon-coaxil-tatinol-tianeptine">Stablon - Coaxil - Tatinol (tianeptine)</category>
 <category domain="http://autism.healingthresholds.com/therapy/therapy">therapy</category>
 <pubDate>Fri, 13 Jun 2008 14:32:52 +0000</pubDate>
 <dc:creator>scottie</dc:creator>
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