Autism Therapy: study design

definition of study design: before scientists begin a research project, they must plan each step of the experiment; that is, they must create the study design. Think of a study design as a map for the scientist to follow

Study Design Overview

Published Oct 31, 2009, last updated Nov 30, 2009

Scientific experiments are designed, not to prove a therapy works, but rather to put a therapy under a hard test to see if even the most suspicious observer could be convinced that the therapy works. The study design is important, because if the design is poor, the results will be difficult to interpret and will not persuade the suspicious observer. Most studies described on this site are designed to test the effect of a given therapy on a population of children with autism. Ideally, the scientists must state the effect that they are looking for prior to beginning the study. The study then measures whether or not this beneficial effect happens, and whether or not there are any unintended harmful effects of the therapy. Most scientists believe that studies with large numbers of subjects (greater than 100) are more reliable than studies with smaller number of subjects. Other important aspects of study design are whether or not the study includes a placebo or other control.

The best study designs are made by people who truly question whether or not a certain therapy works and really want to put the therapy to the test. The worst study designs come from those who already believe that the therapy works and are trying to create more believers through the use of a false version of the scientific process.

Behavior Research Methods, by Anson, HM, Todd JT, and Cassaretto KJ, published in 2008, summarized Dec 22, 2008

Vibrating pagers may be a good tool for prompting children to stay on-task in the classroom.

This study was designed to see if vibrating pagers could be used as a hidden prompt for on-task behavior in a first grade classroom. The authors found that the pager was a good prompt to help children with autism in a classroom setting. The pager was able to reduce the need for overt teacher prompting as required during applied behavior analysis (ABA therapy). The pager was also good because it allowed the prompt to be given even if the teacher was across the room from the child. The authors note that the study design used a "whole-interval recording procedure" which may not have allowed for a good count of the amount of problem behavior.


Autism, by Rust, J., and Smith A., published in 2007, summarized Feb 14, 2008

Social stories may help children with autism learn appropriate behaviors.

Social stories tell children what should happen in a situation, and when, how, and why it should happen. Different social stories describe different situations. This article described studies that have tested whether social stories are helping children with autism. Social stories were originally designed for high-functioning children with autism, but the tool has been tried with children with more severe learning difficulties. The authors said that social stories can be helpful, but it is important to consider each child's skills when deciding whether to use it for that child with autism. The authors suggested improvements for study design in future research on this question.


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