Autism Therapy: tardive dyskinesia

definition of tardive dyskinesia: not yet defined.

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Effects of Development on Olanzapine-Associated Adverse Events
J. Am. Acad. Child Adolesc. Psychiatry, by Woods, SW, Martin A., Spector SG, and McGlashan TH, published in 2002, summarized Dec 8, 2006

Olanzapine may cause weight gain and sedation in children.

Olanzapine is an atypical antipsychotic that is increasingly prescribed to children and teenagers with pervasive developmental disorders, obsessive-compulsive disorder, and mental retardation. This study was designed to determine whether or not there are any side effects from olanzapine that are specific to children and adolescents (as opposed to adults). The authors found that weight gain and sedation may occur more often in children and teenagers than in adults. In addition, children may have more tardive dyskinesia than adults. Tardive dyskinesia is the medical term for repetitive and involuntary movements. The authors suggest that doctors look closely for these side effects in children given olanzapine.


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Clozapine: Food and Drug Administration Safety Labeling Change

Sep 15, 2008

Treatment with the atypical antipsychotic clozapine (FazaClo) may cause uncontrolled movements (tardive dyskinesia). Tardive dyskinesia is a series of uncontrolled movements such as sticking out the tongue, chewing or sucking motions, or making faces. Clozapine may also cause dystonia. Dystonia is a slow movement of a part of the body. In this case, the parts of the body most likely to have the movement are the neck, throat, and tongue. This may cause problems with swallowing and/or breathing. Dystonia is most common in younger children and males.

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